Benzoyl Peroxide
Treatment for Acne
Typical Dosage: Applied once or twice daily (2.5-10%)
Effectiveness
70%
Safety Score
80%
Clinical Trials
179
Participants
50K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
80
DangerousModerateSafe
Treatment Details
Dosage Range
Applied once or twice daily (2.5-10%)
Time to Effect
2-5 weeks
Treatment Duration
Long-term (years)
Evidence Quality
HIGHNumber Needed to Treat (NNT)
7(Treat 7 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
7(Treat 7 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$30
Monitoring:$300
Side Effect Mgmt:$20
Total Annual:$350
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.05
Outcome-Based Costs
Cost per Responder
$76.92
Cost per Remission
$111.11
Benzoyl Peroxide Outcomes
for Acne
Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+65%
Remission Rate
+45%
Common Side Effects
Dryness
+20%
Redness
+20%
Peeling
+15%
Irritation
+10%
Bleaching fabric
+50%
Active Clinical Trials
1 active trial recruiting for Benzoyl Peroxide in Acne
Optimization of Skin Preparation to Reduce Cutibacterium Acnes Colonization in Superficial and Deep Samples During Prosthetic Shoulder Surgery in Male Patients
NCT04028401RECRUITINGPHASE3
110 participants
INTERVENTIONAL
Angers, France +5 more
Started: Jun 19, 2020
Completed Clinical Trials
17 completed trials for Benzoyl Peroxide in Acne
Measuring Adherence in Subjects With Acne Vulgaris in a Clinic Population Subtitle: Topical Benzoyl Peroxide for Acne
NCT00658112COMPLETEDPHASE4
20 participants
INTERVENTIONAL
Winston-Salem, United States
Started: Jul 1, 2006
Long-term Study of Efficacy/Safety of Adapalene/Benzoyl Peroxide Topical Gel in Acne Vulgaris Subjects
NCT00446043COMPLETEDPHASE3
452 participants
INTERVENTIONAL
Portland, United States
Started: Feb 17, 2004
A Comparative Study of the Tolerability of Two Combination Therapies for the Treatment of Acne
NCT00887484COMPLETEDPHASE4
50 participants
INTERVENTIONAL
Ciudad Autonoma de Buenos Aires, Argentina +3 more
Started: Feb 1, 2009
Study of Benzoyl Peroxide Cream for Mild to Moderate Acne Vulgaris
NCT00558831COMPLETEDNA
11 participants
INTERVENTIONAL
Chicago, United States
Started: Oct 1, 2007
A Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris
NCT00421993COMPLETEDPHASE3
1.67K participants
INTERVENTIONAL
Huntsville, United States +61 more
Started: Oct 1, 2006
Comparative Efficacy and Safety of Benzoyl Peroxide Used in Combination With Clindamycin vs. Benzoyl Peroxide Used in Combination With Clindamycin and Doxycycline in the Treatment of Moderate Acne
NCT00837213COMPLETEDPHASE4
33 participants
INTERVENTIONAL
Fremont, United States +1 more
Started: Aug 1, 2007
Two-week Study to Compare the Tolerance and Irritation Potential of Two Combination Topical Gel Acne Medications
NCT00926367COMPLETEDPHASE4
52 participants
INTERVENTIONAL
Broomall, United States
Started: May 1, 2009
Clinical Efficacy Evaluation of a Skincare Product for Acne Face, Upper Chest and Back Used by Multiphototype Population Under Dermatological Control
NCT06786442COMPLETEDNA
130 participants
INTERVENTIONAL
Rio de Janeiro, Brazil
Started: Nov 1, 2023
Japanese Phase 1 Study of GSK2585823
NCT01428466COMPLETEDPHASE1
20 participants
INTERVENTIONAL
Tokyo, Japan
Started: Nov 18, 2010
Effect of Samples on Acne Treatment With Epiduo® Gel
NCT01504204COMPLETEDPHASE4
20 participants
INTERVENTIONAL
Winston-Salem, United States
Started: Dec 1, 2011
Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris
NCT00422240COMPLETEDPHASE3
1.67K participants
INTERVENTIONAL
San Antonio, United States
Started: Jun 27, 2006
Profiling the Skin Microbiome in Response to Altreno in Acne Patients
NCT04548349COMPLETEDPHASE4
25 participants
INTERVENTIONAL
Boston, United States
Started: Apr 23, 2021
Study of Two Different 10.0% Benzoyl Peroxide Creams for Mild to Moderate Acne Vulgaris
NCT00787943COMPLETEDNA
10 participants
INTERVENTIONAL
Chicago, United States
Started: May 1, 2008
BPO vs Hibiclens Soap for Surgical Preparation
NCT04021524COMPLETEDPHASE4
50 participants
INTERVENTIONAL
Seattle, United States
Started: Sep 10, 2018
Double-blind Placebo-controlled Trial of Generic Clindamycin/Benzoyl Peroxide Gel Versus Onexton Gel in Acne Vulgaris
NCT02616614COMPLETEDPHASE3
862 participants
INTERVENTIONAL
Phoenix, United States +16 more
Started: May 1, 2015
A Study of Different Use Regimens Using Two Acne Treatments
NCT00907257COMPLETEDPHASE4
247 participants
INTERVENTIONAL
Boca Raton, United States +11 more
Started: Feb 1, 2009
Efficacy and Safety Study of 2 Different Concentrations of CD1579 Gels Versus Vehicle in the Treatment of Acne Vulgaris.
NCT02073461COMPLETEDPHASE2
236 participants
INTERVENTIONAL
Fukuoka, Japan +5 more
Started: Mar 1, 2014
Showing 20 of 180 total trials