Oral Antibiotics (e.g., Doxycycline)
Treatment for Acne
Typical Dosage: Doxycycline 20mg BID or 50-100mg daily/BID
Effectiveness
68%
Safety Score
65%
Clinical Trials
400
Participants
40K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
Doxycycline 20mg BID or 50-100mg daily/BID
Time to Effect
3-6 weeks
Treatment Duration
3-6 months (limited)
Evidence Quality
MODERATENumber Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
7(Treat 7 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$250
Monitoring:$200
Side Effect Mgmt:$50
Total Annual:$500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEQALYs Gained
0.05
Outcome-Based Costs
Cost per Responder
$769.23
Cost per Remission
$3,333.33
Comparison vs Topical therapy alone
Cost Difference
+$200/year
More expensive
QALY Difference
+0.02 QALYs
Better outcomes
Dominance
No dominance
Oral Antibiotics (e.g., Doxycycline) Outcomes
for Acne
Efficacy Outcomes
Overall Effectiveness
+68%
Response Rate
+65%
Remission Rate
+15%
Common Side Effects
GI upset/nausea
+20%
Photosensitivity
+15%
Vaginal candidiasis
+10%
Antibiotic resistance
+5%
Esophageal irritation
+1%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov