DFDA

Pentamidine

Treatment for African Trypanosomiasis

Typical Dosage: 4 mg/kg IM or IV daily for 7-10 days

Effectiveness
95%
Safety Score
60%
Clinical Trials
1
Participants
5K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
4 mg/kg IM or IV daily for 7-10 days
Time to Effect
Within days, full effect after treatment completion
Treatment Duration
7-10 days
Evidence Quality
HIGH
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$200
Monitoring:$700
Side Effect Mgmt:$100
Total Annual:$1,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
QALYs Gained
3.5
Outcome-Based Costs
Cost per Responder
$1,053
Cost per Remission
$1,111
Pentamidine Outcomes

for African Trypanosomiasis

Efficacy Outcomes
Overall Effectiveness
+95%
Response Rate
+95%
Remission Rate
+90%
Common Side Effects
Hypotension
+40%
Hypoglycemia
+20%
Nephrotoxicity
+7%
Abdominal pain
+15%

Sources:

mdpi.com
nih.gov
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
1 completed trial for Pentamidine in African Trypanosomiasis

Trial of DB289 for the Treatment of Stage I African Trypanosomiasis

NCT00803933COMPLETEDPHASE2
View Study
111 participants
INTERVENTIONAL
Gombé, Republic of the Congo +1 more
Started: Feb 1, 2003