DFDA

Suramin

Treatment for African Trypanosomiasis

Typical Dosage: Test dose 100-200 mg IV, then 20 mg/kg IV on days 1, 3, 7, 14, 21

Effectiveness
95%
Safety Score
55%
Clinical Trials
1
Participants
3K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
55
DangerousModerateSafe
Treatment Details
Dosage Range
Test dose 100-200 mg IV, then 20 mg/kg IV on days 1, 3, 7, 14, 21
Time to Effect
Within days, full effect after treatment completion
Treatment Duration
5-7 weeks
Evidence Quality
HIGH
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$400
Monitoring:$1,500
Side Effect Mgmt:$200
Total Annual:$2,100
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
QALYs Gained
3.5
Outcome-Based Costs
Cost per Responder
$2,211
Cost per Remission
$2,333
Suramin Outcomes

for African Trypanosomiasis

Efficacy Outcomes
Overall Effectiveness
+95%
Response Rate
+95%
Remission Rate
+90%
Common Side Effects
Renal toxicity
+15%
Peripheral neuropathy
+7%
Hypersensitivity reactions
+5%
Nausea
+20%
Fever
+25%

Sources:

cdc.gov
nih.gov
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
1 completed trial for Suramin in African Trypanosomiasis

A Retrospective Analysis of Suramin Treatment for Stage 1 TBR

NCT06060600COMPLETED
View Study
345 participants
OBSERVATIONAL
Tarrytown, United States
Started: Jan 2, 2023