Spironolactone
Treatment for Alcoholic Cardiomyopathy
Typical Dosage: 12.5-25mg daily, titrated to 50mg daily
Effectiveness
70%
Safety Score
65%
Clinical Trials
1
Participants
15K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
12.5-25mg daily, titrated to 50mg daily
Time to Effect
4-8 weeks
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
20(Treat 20 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$80
Monitoring:$400
Side Effect Mgmt:$100
Total Annual:$580
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$10,000/QALY
QALYs Gained
0.5
Outcome-Based Costs
Cost per Responder
$1,055
Comparison vs Placebo
Cost Difference
+$580/year
More expensive
QALY Difference
+0.50 QALYs
Better outcomes
Dominance
No dominance
Spironolactone Outcomes
for Alcoholic Cardiomyopathy
Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+55%
Common Side Effects
Hyperkalemia
+12%
Gynecomastia
+7%
Hypotension
+5%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov