Fluticasone propionate
Treatment for Asthma
Typical Dosage: 88-440 mcg daily
Effectiveness
85%
Safety Score
50%
Clinical Trials
394
Participants
100K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
50
DangerousModerateSafe
Treatment Details
Dosage Range
88-440 mcg daily
Time to Effect
1-2 weeks
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
6(Treat 6 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
100(Treat 100 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$450
Monitoring:$500
Side Effect Mgmt:$50
Total Annual:$1,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$15,000/QALY
QALYs Gained
0.1
Outcome-Based Costs
Cost per Responder
$1,333
Cost per Remission
$2,857
Fluticasone propionate Outcomes
for Asthma
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+75%
Remission Rate
+35%
Common Side Effects
Oropharyngeal candidiasis (thrush)
+7%
Hoarseness/Dysphonia
+7%
Cough
+5%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
19 completed trials for Fluticasone propionate in Asthma
A 12-Week Study To Assess The Safety Of Fluticasone Propionate/Salmeterol 100/50 Hydrofluoroalkane (HFA) Versus Fluticasone Propionate 100 HFA In Children With Asthma
NCT00441441COMPLETEDPHASE3
351 participants
INTERVENTIONAL
Huntington Beach, United States +54 more
Started: Feb 1, 2007
Seretide Versus Flixotide In Asthmatic Children Not Controlled By Inhaled Corticosteroids
NCT00353873COMPLETEDPHASE4
506 participants
INTERVENTIONAL
Bruges, Belgium +64 more
Started: Nov 18, 2005
Dose Response of Fractional Exhaled Nitric Oxide (FeNO) to Inhaled Steroids in Mild-to-moderate Asthma
NCT00995657COMPLETEDPHASE4
21 participants
INTERVENTIONAL
Dundee, United Kingdom
Started: Oct 1, 2009
Childhood Asthma Research and Education (CARE) Network Trial - Best Add-On Therapy Giving Effective Response (BADGER)
NCT00395304COMPLETEDPHASE3
182 participants
INTERVENTIONAL
Tucson, United States +4 more
Started: Mar 1, 2007
Post-marketing Safety Monitoring Program of Fluticasone Propionate (FP) in Chinese Subjects With Asthma Aged 1 to <4 Years
NCT03273946COMPLETED
158 participants
OBSERVATIONAL
Shenzhen, China +3 more
Started: Jan 9, 2018
Study to Determine the Pharmacokinetics and Tolerability of Fluticasone Propionate MDPI and Fluticasone Propionate/Salmeterol MDPI Compared to High Strength FLOVENT® DISKUS® and ADVAIR® DISKUS® in Patients With Persistent Asthma 12 Years of Age and Older
NCT02437604COMPLETEDPHASE1
43 participants
INTERVENTIONAL
Raleigh, United States +2 more
Started: May 1, 2015
Evaluating the Efficacy and Safety of Fluticasone Furoate Inhalation Powder in the Treatment of Asthma in Adults and Adolescents
NCT01159912COMPLETEDPHASE3
350 participants
INTERVENTIONAL
Birmingham, United States +81 more
Started: Jun 30, 2010
Sensitivity of Pharmacokinetics to Differences in Aerodynamic Particle Size Distribution
NCT01966692COMPLETEDPHASE1
24 participants
INTERVENTIONAL
Gainesville, United States
Started: Nov 1, 2016
Study In Airway Physiology In Children SERETIDE DISKUS ® Inhlaer and FLIXOTIDE® Inhaler Are Trademarks of GSK Group of Companies.
NCT00169546COMPLETEDPHASE4
64 participants
INTERVENTIONAL
Wellington, New Zealand +1 more
Started: Jan 1, 2003
Study of Fluticasone Propionate Multidose Dry Powder Inhaler Compared With Fluticasone Propionate/Salmeterol Multidose Dry Powder Inhaler
NCT02980133COMPLETEDPHASE3
841 participants
INTERVENTIONAL
Birmingham, United States +117 more
Started: Dec 28, 2016
The Effects of Montelukast on Smokers With Asthma
NCT00712335COMPLETEDPHASE4
105 participants
INTERVENTIONAL
Seoul, South Korea
Started: Feb 1, 2007
A Study to Compare the Efficacy and Safety of Fluticasone Furoate (FF) 100 mcg Once Daily With Fluticasone Propionate (FP) 250 mcg Twice Daily (BD) and FP 100 mcg BD in Well-controlled Asthmatic Japanese Subjects
NCT02094937COMPLETEDPHASE3
430 participants
INTERVENTIONAL
Aomori, Japan +32 more
Started: Mar 27, 2014
12-Week Study in Adult Subjects With Asthma
NCT01516073COMPLETEDPHASE2
629 participants
INTERVENTIONAL
Greenville, United States
Started: Mar 1, 2012
A Double Blind Open Label Comparator Study to Compare Treatments in 4 to 11 Year Old Patients With Asthma
NCT02680561COMPLETEDPHASE1
20 participants
INTERVENTIONAL
Huntington Beach, United States +2 more
Started: Apr 1, 2016
Study Of Patients With Allergic Rhinitis And Asthma
NCT00296530COMPLETEDPHASE4
600 participants
INTERVENTIONAL
Ozark, United States +79 more
Started: Sep 1, 2005
A Dose-ranging Study of Fluticasone Furoate (FF)
NCT01563029COMPLETEDPHASE2
597 participants
INTERVENTIONAL
Little Rock, United States +138 more
Started: Mar 28, 2012
Clinical Assessment Of GW815SF HFA MDI In Pediatric Patients With Bronchial Asthma
NCT00448435COMPLETEDPHASE3
51 participants
INTERVENTIONAL
Chiba, Japan +7 more
Started: Apr 1, 2007
Study on the Effects of an AMP Challenge on Asthmatic Patients Following Treatment With Fluticasone Propionate
NCT00400855COMPLETEDPHASE2
49 participants
INTERVENTIONAL
Christchurch, New Zealand +1 more
Started: Jan 1, 2005
Pediatric Asthma Study Using Stepwise Treatment With Two Food And Drug Administration Approved Asthma Medications
NCT00158834COMPLETEDPHASE3
200 participants
INTERVENTIONAL
Alkmaar, Netherlands +15 more
Started: Nov 1, 1999
Showing 20 of 398 total trials