Radical Cystectomy
Treatment for Bladder Cancer
Effectiveness
85%
Safety Score
35%
Clinical Trials
270
Participants
30K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
35
DangerousModerateSafe
Treatment Details
Time to Effect
immediate
Treatment Duration
One-time surgery + lifelong management of diversion
Evidence Quality
HIGHNumber Needed to Harm (NNH)
2(Treat 2 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$100,000
Monitoring:$7,000
Side Effect Mgmt:$10,000
Total Annual:$117,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$80,000/QALY
QALYs Gained
3
Outcome-Based Costs
Cost per Responder
$137,647.06
Cost per Remission
$195,000
Radical Cystectomy Outcomes
for Bladder Cancer
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+85%
Remission Rate
+60%
Common Side Effects
Post-operative complications (infection, bleeding, ileus)
+50%
Urinary diversion complications (stoma issues, metabolic acidosis)
+30%
Sexual dysfunction (erectile dysfunction, vaginal shortening)
+90%
Perioperative mortality
+3%
Active Clinical Trials
8 active trials recruiting for Radical Cystectomy in Bladder Cancer
Robotic Radical Cystectomy Outcomes
NCT04900558RECRUITING
500 participants
OBSERVATIONAL
Florence, Italy
Started: Apr 29, 2021
Study on the Quality of Life and Pathological State in Patients Who Underwent Radical Cystectomy
NCT06170177RECRUITING
4K participants
OBSERVATIONAL
Milan, Italy
Started: Feb 4, 2013
Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy
NCT05792722RECRUITINGNA
70 participants
INTERVENTIONAL
Washington D.C., United States +1 more
Started: Oct 25, 2023
Radical CystEctomy or RaDio-chEMotherapy as Preferred Treatment for invasivE blaDder Cancer
NCT07008833NOT YET RECRUITINGNA
336 participants
INTERVENTIONAL
São Paulo, Brazil
Started: Jun 1, 2025
Cystoscopic Evaluation Predicting pT0 Urothelial Carcinoma of the Bladder
NCT02968732ACTIVE NOT RECRUITINGNA
65 participants
INTERVENTIONAL
Philadelphia, United States
Started: Nov 11, 2016
Neoadjuvant Adebrelimab Plus Etoposide and Cisplatin in Neuroendocrine Bladder Carcinoma
NCT06091124RECRUITINGPHASE2
22 participants
INTERVENTIONAL
Nanjing, China +4 more
Started: Nov 16, 2023
RC48 Combined with Toripalimab As Neoadjuvant Therapy for Cisplatin Ineligible MIBC Patients
NCT06341400RECRUITINGPHASE1, PHASE2
55 participants
INTERVENTIONAL
Guangzhou, China
Started: Jun 19, 2024
Assessment of Decision Tool to Select Women for Gynecologic Sparing Radical Cystectomy
NCT06184516RECRUITINGPHASE2
147 participants
INTERVENTIONAL
Gainesville, United States
Started: Aug 30, 2024
Completed Clinical Trials
6 completed trials for Radical Cystectomy in Bladder Cancer
Study Comparing Open Radical Cystectomy With Robot-assisted Cystectomy in Patients With Bladder Cancer
NCT03977831COMPLETEDNA
50 participants
INTERVENTIONAL
Copenhagen, Denmark
Started: Jun 6, 2019
Enhanced Recovery After Radical Cystectomy Study
NCT02328417COMPLETED
241 participants
OBSERVATIONAL
Alcalá de Henares, Spain +11 more
Started: Dec 1, 2014
Neoadjuvant Dasatinib and Radical Cystectomy for Transitional Cell Carcinoma of the Bladder
NCT00706641COMPLETEDNA
25 participants
INTERVENTIONAL
Indianapolis, United States +2 more
Started: Jun 1, 2008
Randomized Trial Comparing Robotic and Open Radical Cystectomy
NCT01076387COMPLETEDPHASE3
124 participants
INTERVENTIONAL
New York, United States
Started: Feb 1, 2010
Trial of Open Versus Laparoscopic Radical Cystectomy at a Laparoscopic Naive Center
NCT04838873COMPLETEDNA
60 participants
INTERVENTIONAL
Cairo, Egypt
Started: Jan 24, 2019
Erlotinib Before and After Surgery in Treating Patients With Muscle-Invasive Bladder Cancer
NCT00380029COMPLETEDPHASE2
27 participants
INTERVENTIONAL
Chapel Hill, United States
Started: May 1, 2006
Showing 20 of 278 total trials