Radiation Therapy
Treatment for Breast Cancer
Typical Dosage: Typically 40-50 Gy in 15-25 fractions, or hypofractionated regimens
Effectiveness
75%
Safety Score
25%
Clinical Trials
1,471
Participants
120K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
25
DangerousModerateSafe
Treatment Details
Dosage Range
Typically 40-50 Gy in 15-25 fractions, or hypofractionated regimens
Time to Effect
Weeks to months post-treatment
Treatment Duration
3-6 weeks
Evidence Quality
HIGHNumber Needed to Treat (NNT)
10(Treat 10 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
5(Treat 5 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$2,000
Side Effect Mgmt:$1,000
Total Annual:$60,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$60,000/QALY
QALYs Gained
0.8
Outcome-Based Costs
Cost per Responder
$75,000
Cost per Remission
$120,000
Radiation Therapy Outcomes
for Breast Cancer
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+80%
Remission Rate
+50%
Common Side Effects
Skin irritation/redness
+85%
Fatigue
+70%
Breast pain/swelling
+50%
Lung inflammation (radiation pneumonitis)
+5%
Lymphedema
+10%
Active Clinical Trials
12 active trials recruiting for Radiation Therapy in Breast Cancer
Partial Breast Re-irradiation for Breast Cancer
NCT06954623RECRUITINGPHASE2
20 participants
INTERVENTIONAL
Heidelberg, Germany
Started: Aug 28, 2025
Hypofractionated Online Adaptive Radiotherapy of Breast Cancer
NCT06568705RECRUITINGPHASE2
40 participants
INTERVENTIONAL
Beijing, China
Started: Sep 1, 2024
Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast
NCT06129747RECRUITINGPHASE2
55 participants
INTERVENTIONAL
Cleveland, United States +1 more
Started: Nov 30, 2023
Omission of Local Therapies in Women Patients With HER2-positive or Triple-negative Breast Cancer
NCT06938724RECRUITINGPHASE2
152 participants
INTERVENTIONAL
Milan, Italy
Started: Jul 25, 2025
5 vs. 9-day Course of Whole Breast Radiotherapy With Boost for Early-stage Breast Cancer
NCT06961955RECRUITINGPHASE2
144 participants
INTERVENTIONAL
Salt Lake City, United States
Started: May 21, 2025
Efficacy and Safety of Ultra_HYPofractionated RadiotHerapy in Women With BrEast CaNcer Receiving Regional Nodal Radiation vs Nodal Moderate Hypofractionated Radiotherapy
NCT05665920RECRUITINGNA
36 participants
INTERVENTIONAL
São Paulo, Brazil
Started: Oct 18, 2022
Hypofractionated LocoRegional Radiotherapy in Breast Cancer
NCT04228991ACTIVE NOT RECRUITINGPHASE3
588 participants
INTERVENTIONAL
Calgary, Canada +19 more
Started: Feb 10, 2021
Temporal Immunologic Changes With Hypofractionated Radiation-Induced DNA Damage in Breast Cancer
NCT05406232RECRUITING
12 participants
OBSERVATIONAL
Houston, United States
Started: Sep 15, 2023
Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer
NCT03936478RECRUITINGPHASE2
30 participants
INTERVENTIONAL
Madison, United States
Started: May 16, 2022
SBRT in Early Breast Cancer in Elderly Women
NCT05071105RECRUITINGNA
30 participants
INTERVENTIONAL
Rome, Italy
Started: Jan 1, 2021
Study of Radiation Fractionation on Patient Outcomes After Breast REConstruction (FABREC) for Invasive Breast Carcinoma
NCT03422003ACTIVE NOT RECRUITINGNA
400 participants
INTERVENTIONAL
San Francisco, United States +14 more
Started: Apr 1, 2018
Shorter Course Radiation for the Treatment of Breast Cancer That Has Spread to Lymph Nodes
NCT02700386ACTIVE NOT RECRUITINGPHASE2
108 participants
INTERVENTIONAL
Aurora, United States +2 more
Started: Aug 11, 2016
Completed Clinical Trials
3 completed trials for Radiation Therapy in Breast Cancer
Three Dimensional (3D) Ultrasound in Predicting Response to Breast Cancer Therapies
NCT00721903COMPLETEDNA
88 participants
INTERVENTIONAL
Ann Arbor, United States
Started: Mar 1, 2000
Adjuvant Hypofractionated Intensity-Modulated Radiation Therapy With Incorporated Boost in Treating Patients With Early-Stage Breast Cancer
NCT00084539COMPLETEDPHASE2
78 participants
INTERVENTIONAL
Philadelphia, United States
Started: Nov 1, 2003
Cytokine Expression During Radiation for Breast Cancer
NCT00836186COMPLETEDNA
82 participants
INTERVENTIONAL
Baltimore, United States +1 more
Started: Nov 13, 2009
Showing 20 of 1482 total trials