Corticosteroid Injection (e.g., Methylprednisolone)
Treatment for Carpal Tunnel Syndrome
Typical Dosage: 10-20 mg Methylprednisolone or equivalent, mixed with local anesthetic
Effectiveness
80%
Safety Score
70%
Clinical Trials
200
Participants
20K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
10-20 mg Methylprednisolone or equivalent, mixed with local anesthetic
Time to Effect
24-72 hours
Treatment Duration
Single injection, effects last 1-6 months; repeat injections discouraged
Evidence Quality
HIGHNumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
150(Treat 150 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$50
Monitoring:$300
Side Effect Mgmt:$50
Total Annual:$400
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODQALYs Gained
0.2
Outcome-Based Costs
Cost per Responder
$533
Cost per Remission
$1,000
Comparison vs Oral Corticosteroids
Cost Difference
+$100/year
More expensive
QALY Difference
+0.05 QALYs
Better outcomes
Dominance
No dominance
Corticosteroid Injection (e.g., Methylprednisolone) Outcomes
for Carpal Tunnel Syndrome
Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+75%
Remission Rate
+40%
Common Side Effects
Injection site pain/bruising
+15%
Local skin atrophy/depigmentation
+7%
Infection
+0.5%
Temporary flare of symptoms
+3%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov