DFDA

Night Splinting / Wrist Bracing

Treatment for Carpal Tunnel Syndrome

Typical Dosage: Wear at night and/or during aggravating activities

Effectiveness
70%
Safety Score
95%
Clinical Trials
2
Participants
15K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
95
DangerousModerateSafe
Treatment Details
Dosage Range
Wear at night and/or during aggravating activities
Time to Effect
Few days to 2 weeks
Treatment Duration
Typically 4-12 weeks initially, then as needed for recurrence, often long-term night use
Evidence Quality
HIGH
Number Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$100
Side Effect Mgmt:$0
Total Annual:$200
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
QALYs Gained
0.1
Outcome-Based Costs
Cost per Responder
$308
Cost per Remission
$667
Comparison vs Carpal Tunnel Release Surgery
Cost Difference
$-6,800/year
Less expensive
QALY Difference
-0.40 QALYs
Worse outcomes
Dominance
No dominance
Night Splinting / Wrist Bracing Outcomes

for Carpal Tunnel Syndrome

Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+65%
Remission Rate
+30%
Common Side Effects
Skin irritation/discomfort
+10%
Impaired sleep (initial)
+3%

Sources:

keele.ac.uk
nih.gov
cochrane.org

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
1 active trial recruiting for Night Splinting / Wrist Bracing in Carpal Tunnel Syndrome

Efficacy of Laser Acupuncture on Carpal Tunnel Syndrome Following Hand Flexor Tendon Repair

NCT07014774NOT YET RECRUITINGNA
View Study
60 participants
INTERVENTIONAL
Cairo, Egypt
Started: Jun 15, 2025
Completed Clinical Trials
1 completed trial for Night Splinting / Wrist Bracing in Carpal Tunnel Syndrome

Effect of Neurodynamic Exercises and Education Program Applied With Virtual Reality Assisted Telerehabilitation Method in Conservative Treatment of Carpal Tunnel Syndrome

NCT05821127COMPLETEDNA
View Study
60 participants
INTERVENTIONAL
Istanbul, Turkey (Türkiye)
Started: Apr 15, 2023