Oral Corticosteroids (e.g., Prednisone)
Treatment for Carpal Tunnel Syndrome
Typical Dosage: e.g., Prednisone 20 mg daily for 2 weeks, then taper
Effectiveness
65%
Safety Score
50%
Clinical Trials
50
Participants
5K
Comparative Safety Scale(Higher is safer)
Cyanideâ ī¸
Methđ
CigarettesđŦ
Chemoâĸī¸
Alcoholđē
Morphineđ
Antibioticsđ
Tylenolđ
Exerciseđ
Waterđ§
50
DangerousModerateSafe
Treatment Details
Dosage Range
e.g., Prednisone 20 mg daily for 2 weeks, then taper
Time to Effect
24-48 hours
Treatment Duration
Short course, typically 2-4 weeks with tapering
Evidence Quality
MODERATENumber Needed to Treat (NNT)
6(Treat 6 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
75%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$50
Monitoring:$100
Side Effect Mgmt:$50
Total Annual:$200
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODQALYs Gained
0.08
Outcome-Based Costs
Cost per Responder
$308
Cost per Remission
$800
Comparison vs Corticosteroid Injection
Cost Difference
$-100/year
Less expensive
QALY Difference
-0.05 QALYs
Worse outcomes
Dominance
No dominance
Prescription Access Economics
Oral Corticosteroids (e.g., Prednisone) Outcomes
for Carpal Tunnel Syndrome
Efficacy Outcomes
Overall Effectiveness
+65%
Response Rate
+65%
Remission Rate
+25%
Common Side Effects
Insomnia, mood changes
+15%
Fluid retention, weight gain
+10%
Increased appetite
+7%
Gastric irritation
+3%
Increased blood sugar
+3%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov