Gluten-Free Diet (GFD)
Treatment for Celiac Disease
Typical Dosage: Strict avoidance of all gluten-containing foods
Effectiveness
95%
Safety Score
95%
Clinical Trials
21
Participants
0
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
95
DangerousModerateSafe
Treatment Details
Dosage Range
Strict avoidance of all gluten-containing foods
Time to Effect
Weeks to months for symptom resolution and mucosal healing
Treatment Duration
Lifetime
Evidence Quality
HIGHConfidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$700
Side Effect Mgmt:$200
Total Annual:$2,400
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
2.5
Outcome-Based Costs
Cost per Responder
$2,823
Cost per Remission
$3,428
Gluten-Free Diet (GFD) Outcomes
for Celiac Disease
Efficacy Outcomes
Overall Effectiveness
+95%
Response Rate
+85%
Remission Rate
+70%
Common Side Effects
Nutritional deficiencies (e.g., iron, vitamin D, folate)
+30%
Social and psychological burden
+50%
Increased cost of gluten-free foods
+100%
Accidental gluten exposure leading to symptoms
+40%
Sources:
Active Clinical Trials
6 active trials recruiting for Gluten-Free Diet (GFD) in Celiac Disease
Inflammatory Back Pain and Gluten Free Diet
NCT03017716NOT YET RECRUITINGNA
50 participants
INTERVENTIONAL
Sciacca, Italy +1 more
Started: Jul 1, 2026
GF-NOURISH (Gluten Free Nutrition Optimization Through Ultra-processed Food Reduction and Improved Strategies for Health)
NCT06356220RECRUITINGNA
120 participants
INTERVENTIONAL
Boston, United States
Started: Apr 29, 2025
Liver Steatosis in Pediatric CD Patients
NCT06206616NOT YET RECRUITING
91 participants
OBSERVATIONAL
Palermo, Italy +1 more
Started: Nov 1, 2025
Influence of a Gluten Free Food Guide on Diet Quality and Adherence to the GFD in Youth With Celiac Disease
NCT06038344ACTIVE NOT RECRUITINGNA
40 participants
INTERVENTIONAL
Edmonton, Canada
Started: Jun 22, 2021
Entities and Variables Related to Catch-up Growth
NCT06364735RECRUITING
900 participants
OBSERVATIONAL
Milan, Italy
Started: Jul 1, 2024
Evaluation of the Effects of Gluten Free Diet on Clinical Symptoms and Glycemic Index in Type 2 Diabetic Patients With Non-celiac Gluten Sensitivity
NCT06900946ENROLLING BY INVITATIONNA
50 participants
INTERVENTIONAL
Tehran, Iran
Started: Apr 1, 2025
Completed Clinical Trials
12 completed trials for Gluten-Free Diet (GFD) in Celiac Disease
Gluten-free Diet Monitoring in Urine
NCT02344758COMPLETEDEARLY_PHASE1
134 participants
INTERVENTIONAL
Seville, Spain
Started: Apr 1, 2013
TCRγδ+ Cells After Gluten-free Diet: A Biomarker for Coeliac Disease?
NCT05733663COMPLETED
116 participants
OBSERVATIONAL
Terrassa, Spain
Started: Jan 1, 2013
Intestinal Permeability, Nutritional Status and Quality of Life in Celiac Disease
NCT04351828COMPLETED
44 participants
OBSERVATIONAL
Istanbul, Turkey (Türkiye)
Started: Nov 5, 2018
INF-α Innate Immune Response to Gliadin
NCT03221647COMPLETED
53 participants
OBSERVATIONAL
Naples, Italy
Started: Jan 10, 2013
Prebiotic as a Supplement of Gluten-free Diet in the Management of Celiac Disease in Children
NCT03064997COMPLETEDNA
34 participants
INTERVENTIONAL
Olsztyn, Poland +1 more
Started: Jan 12, 2016
"Gluten Friendly" Treatment in Celiac Disease
NCT03137862COMPLETEDNA
45 participants
INTERVENTIONAL
San Giovanni Rotondo, Italy
Started: Mar 20, 2017
Quantification of Gluten Peptides in Feces
NCT02711397COMPLETED
272 participants
OBSERVATIONAL
Started: Apr 1, 2012
Characteristics of Anemia in Celiac Disease
NCT05172895COMPLETED
159 participants
OBSERVATIONAL
Sciacca, Italy +2 more
Started: Jan 1, 2001
Educational Intervention on Celiac Disease and Gluten-free Diet Through Social Networks (GLUTLEARN Project).
NCT05923346COMPLETEDNA
93 participants
INTERVENTIONAL
Vitoria-Gasteiz, Spain
Started: Feb 1, 2022
Assessment of the Effect of Gluten Free Toothpaste on the Ulcerative Events in Children With Celiac Disease
NCT03771443COMPLETEDPHASE3
20 participants
INTERVENTIONAL
Giza, Egypt
Started: Jul 21, 2019
Effect of FODMAP Restriction on Persistent GI-symptoms in Coeliac Patients
NCT03678935COMPLETEDNA
80 participants
INTERVENTIONAL
Oslo, Norway
Started: Oct 1, 2018
Use of a Selected Mixture of Probiotic Strains for Degrading Gluten During Digestion
NCT05798689COMPLETEDNA
70 participants
INTERVENTIONAL
Bolzano, Italy
Started: Oct 1, 2020
Showing 20 of 21 total trials