Azithromycin
Treatment for Chlamydial Infection
Typical Dosage: 1g orally in a single dose
Effectiveness
97%
Safety Score
70%
Clinical Trials
47
Participants
1.5M
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
1g orally in a single dose
Time to Effect
Single dose for cure, symptoms improve in days
Treatment Duration
Single dose
Evidence Quality
HIGHNumber Needed to Treat (NNT)
1.03(Treat 1.03 patients to see 1 additional successful outcome)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$15
Monitoring:$600
Side Effect Mgmt:$5
Total Annual:$620
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.08
Outcome-Based Costs
Cost per Responder
$20.62
Cost per Remission
$20.62
Comparison vs Doxycycline
Cost Difference
$-5/year
Less expensive
QALY Difference
0.00 QALYs
Same outcomes
Dominance
No dominance
Prescription Access Economics
Annual Societal Loss per Patient
$-9,777
Cost of prescription-only barriers (visits, time, admin, price premium)
Physician Visit Cost
$150/year
Time Cost
$45/year
Travel + wait time
Insurance Admin Cost
$20/year
Prior auth, claims
Rx Price
$15/year
Potential OTC Price
$7/year
Estimated if OTC available
Early Treatment Benefit
+0.05 QALYs
From faster OTC access
Risk Assessment
Misuse Risk
LOWMissed Diagnosis Risk
LOWAzithromycin Outcomes
for Chlamydial Infection
Efficacy Outcomes
Overall Effectiveness
+97%
Response Rate
+97%
Remission Rate
+97%
Common Side Effects
Nausea
+10%
Diarrhea
+8%
Abdominal pain
+5%
Vomiting
+3%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
16 completed trials for Azithromycin in Chlamydial Infection
YCFM (Youth Correctional Facilities Males)
NCT03249935COMPLETEDPHASE2
100 participants
INTERVENTIONAL
Los Angeles, United States
Started: Aug 24, 2017
Treatment Failure of Chlamydial Infection in Males and Females in Youth Correctional Facilities
NCT00980148COMPLETEDPHASE3
567 participants
INTERVENTIONAL
Birmingham, United States +1 more
Started: Dec 1, 2009
The Effect of Oral Azithromycin in the Treatment of Chlamydial Conjunctivitis
NCT01178762COMPLETEDNA
42 participants
INTERVENTIONAL
Taipei, Taiwan
Started: Sep 1, 2007
Trial of Azithromycin vs. Doxycycline for the Treatment of Rectal Chlamydia in MSM
NCT03608774COMPLETEDPHASE4
177 participants
INTERVENTIONAL
Boston, United States +1 more
Started: Jul 13, 2018
Chlamydia Trachomatis Immunology and Vaccinology Study
NCT01150747COMPLETED
347 participants
OBSERVATIONAL
Pittsburgh, United States +3 more
Started: Jan 1, 2011
Impact of Two Alternative Dosing Strategies for Trachoma Control in Niger
NCT00618449COMPLETEDPHASE4
1.14K participants
INTERVENTIONAL
San Francisco, United States +1 more
Started: Jan 1, 2008
Safety and Efficacy Study of Rifalazil for the Treatment of Chlamydia Trachomatis Infection in Women
NCT01631201COMPLETEDPHASE2
82 participants
INTERVENTIONAL
Birmingham, United States +4 more
Started: Jul 1, 2012
Genital CT Treatment to Pregnant Women to Prevent Adverse Pregnancy Outcomes: A Pilot RCT
NCT03862495COMPLETEDNA
200 participants
INTERVENTIONAL
Guangzhou, China +1 more
Started: May 21, 2020
Tripartite International Research for the Elimination of Trachoma
NCT01202331COMPLETEDPHASE4
29K participants
INTERVENTIONAL
Addis Ababa, Ethiopia
Started: Nov 1, 2010
Trachoma Elimination Follow-up
NCT00221364COMPLETEDPHASE4
20K participants
INTERVENTIONAL
Addis Ababa, Ethiopia
Started: Mar 1, 2003
Trachoma Amelioration in Northern Amhara (TANA)
NCT00322972COMPLETEDPHASE4
33K participants
INTERVENTIONAL
Addis Ababa, Ethiopia
Started: Jun 1, 2006
Incubation Time and Test of Cure of Chlamydia Trachomatis
NCT01448876COMPLETED
52 participants
OBSERVATIONAL
Geleen, Netherlands
Started: Jun 1, 2009
Partnership for Rapid Elimination of Trachoma
NCT00792922COMPLETEDPHASE4
128 participants
INTERVENTIONAL
San Francisco, United States +2 more
Started: May 1, 2008
Antibiotic Treatment Trial Directed Against Chlamydia Pneumonia in Multiple Sclerosis
NCT00043264COMPLETEDPHASE2
40 participants
INTERVENTIONAL
Houston, United States
Expedited Partner Therapy for MSM in Peru
NCT01720654COMPLETEDNA
165 participants
INTERVENTIONAL
Lima, Peru
Started: Aug 1, 2012
Azithromycin Reduction to Reach Elimination of Trachoma
NCT04185402COMPLETEDPHASE4
74.9K participants
INTERVENTIONAL
Niamey, Niger
Started: May 29, 2021
Showing 20 of 47 total trials