Azithromycin
Treatment for Chronic Bronchitis
Typical Dosage: 250 mg 3 times per week, or 500 mg 3 times per week
Effectiveness
60%
Safety Score
50%
Clinical Trials
22
Participants
5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
50
DangerousModerateSafe
Treatment Details
Dosage Range
250 mg 3 times per week, or 500 mg 3 times per week
Time to Effect
Weeks to months
Treatment Duration
6-12 months, or longer
Evidence Quality
MODERATENumber Needed to Treat (NNT)
7(Treat 7 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
10(Treat 10 patients to see 1 additional serious adverse event)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$300
Monitoring:$850
Side Effect Mgmt:$100
Total Annual:$1,250
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$25,000/QALY
QALYs Gained
0.04
Outcome-Based Costs
Cost per Responder
$2,500
Active Clinical Trials
4 active trials recruiting for Azithromycin in Chronic Bronchitis
Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)
NCT04069312ACTIVE NOT RECRUITINGPHASE4
1.03K participants
INTERVENTIONAL
Birmingham, United States +28 more
Started: Feb 11, 2020
Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host Disease
NCT04294641ACTIVE NOT RECRUITINGPHASE2
10 participants
INTERVENTIONAL
Bethesda, United States +1 more
Started: May 10, 2021
BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP)
NCT05922761RECRUITINGPHASE2
45 participants
INTERVENTIONAL
Boston, United States +4 more
Started: May 31, 2024
Evaluation of the Efficacy of Azithromycin in Idiopathic Purulent Oedematous Sinusitis in Adults
NCT05157685RECRUITINGPHASE3
230 participants
INTERVENTIONAL
Bordeaux, France +12 more
Started: Nov 21, 2022
Completed Clinical Trials
11 completed trials for Azithromycin in Chronic Bronchitis
A Study of the Effectiveness and Safety of High Dose, Short-course Levofloxacin in the Treatment of Acute Bacterial Exacerbation (Worsening) of Chronic Bronchitis.
NCT00042718COMPLETEDPHASE3
659 participants
INTERVENTIONAL
Started: Nov 1, 2001
A Trial To Evaluate Two Antibiotics For The Treatment Of Acute Exacerbation Of Chronic Bronchitis (AECB)
NCT00254566COMPLETEDPHASE3
398 participants
INTERVENTIONAL
Guangzhou, China +33 more
Started: Feb 1, 2006
Study of Azithromycin for Lymphocytic Bronchiolitis/Bronchitis After Lung Transplantation
NCT01109160COMPLETEDPHASE4
15 participants
INTERVENTIONAL
Leuven, Belgium
Started: Apr 1, 2010
A Multicentre, Randomised, Open-Label Study To Compare The Efficacy And Safety Of Azithromycin For 5 Days With Those Of Amoxicillin-Clavulanic Acid In Patients With Chronic Bronchitis
NCT00649831COMPLETEDPHASE3
250 participants
INTERVENTIONAL
Anzin, France +30 more
Started: Oct 1, 2002
A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Acute Symptoms of Chronic Bronchitis
NCT00644449COMPLETEDPHASE3
551 participants
INTERVENTIONAL
Birmingham, United States +74 more
Started: Jan 1, 2003
A Trial Of Azithromycin SR For The Treatment Of Acute Bronchitis And Secondary Infection Of Chronic Respiratory Diseases
NCT00360464COMPLETEDPHASE3
64 participants
INTERVENTIONAL
Hitachi-Naka, Japan +18 more
Started: Oct 1, 2006
The Effect of Azithromycin in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Chronic Productive Cough
NCT01071161COMPLETEDPHASE3
84 participants
INTERVENTIONAL
Zwolle, Netherlands
Started: Sep 1, 2009
PERSPECTIVE: Telithromycin - Acute Exacerbation of Chronic Bronchitis
NCT00132938COMPLETEDPHASE4
5.66K participants
INTERVENTIONAL
Bridgewater, United States +7 more
Started: Jan 1, 2004
Telithromycin: in the Treatment of Acute Exacerbation of Chronic Bronchitis in Adult Outpatients With COPD
NCT00538148COMPLETEDPHASE4
668 participants
INTERVENTIONAL
Started: Nov 1, 2002
Standard vs. Biofilm Susceptibility Testing in Cystic Fibrosis (CF)
NCT00153634COMPLETEDNA
75 participants
INTERVENTIONAL
Iowa City, United States +7 more
Started: Mar 1, 2004
Early Detection and Management of Bronchiolitis Obliterans Syndrome Following Pediatric Hematopoietic Stem Cell Transplantation
NCT03072849COMPLETED
23 participants
OBSERVATIONAL
Chicago, United States
Started: Apr 1, 2015
Showing 20 of 22 total trials