DFDA

Amitriptyline

Treatment for Chronic Fatigue Syndrome

Typical Dosage: 10-50mg at bedtime

Effectiveness
45%
Safety Score
60%
Clinical Trials
12
Participants
750

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
10-50mg at bedtime
Time to Effect
2-4 weeks
Treatment Duration
Long-term
Evidence Quality
MODERATE
Confidence Score
70%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$100
Monitoring:$200
Side Effect Mgmt:$75
Total Annual:$375
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$25,000/QALY
QALYs Gained
0.08
Outcome-Based Costs
Cost per Responder
$1,250
Cost per Remission
$18,750
Amitriptyline Outcomes

for Chronic Fatigue Syndrome

Efficacy Outcomes
Overall Effectiveness
+45%
Response Rate
+30%
Remission Rate
+2%
Common Side Effects
Dry mouth
+35%
Drowsiness/Sedation
+25%
Constipation
+20%
Weight gain
+15%
Dizziness
+12%

Sources:

nih.gov
meassociation.org.uk
moregooddays.com

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov