Metformin
Treatment for Chronic Kidney Disease Due To Diabetes Mellitus Type 2
Typical Dosage: 500-2000mg daily
Effectiveness
75%
Safety Score
65%
Clinical Trials
1,000
Participants
5M
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
500-2000mg daily
Time to Effect
1-2 weeks for glycemic control, years for long-term complications
Treatment Duration
lifetime (if eGFR allows)
Evidence Quality
HIGHNumber Needed to Treat (NNT)
25(Treat 25 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
5(Treat 5 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$120
Monitoring:$1,200
Side Effect Mgmt:$50
Total Annual:$1,370
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$10,000/QALY
QALYs Gained
1.8
Outcome-Based Costs
Cost per Responder
$1,522.22
Metformin Outcomes
for Chronic Kidney Disease Due To Diabetes Mellitus Type 2
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+90%
Common Side Effects
Diarrhea
+20%
Nausea
+10%
Abdominal discomfort
+10%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov