Lisinopril (ACE Inhibitor)
Treatment for Chronic Kidney Disease Due To Glomerulonephritis
Typical Dosage: 5-40 mg once daily
Effectiveness
85%
Safety Score
70%
Clinical Trials
500
Participants
200K
Comparative Safety Scale(Higher is safer)
Cyanideâ ī¸
Methđ
CigarettesđŦ
Chemoâĸī¸
Alcoholđē
Morphineđ
Antibioticsđ
Tylenolđ
Exerciseđ
Waterđ§
70
DangerousModerateSafe
Treatment Details
Dosage Range
5-40 mg once daily
Time to Effect
1-3 months for kidney protection
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
12(Treat 12 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
250(Treat 250 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$20
Monitoring:$200
Side Effect Mgmt:$50
Total Annual:$270
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$15,000/QALY
QALYs Gained
1
Outcome-Based Costs
Cost per Responder
$360
Comparison vs No ACE inhibitor/ARB treatment
Cost Difference
$-5,000/year
Less expensive
QALY Difference
+1.00 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
Prescription Access Economics
Physician Visit Cost
$400/year
Time Cost
$160/year
Travel + wait time
Insurance Admin Cost
$40/year
Prior auth, claims
Rx Price
$20/year
Potential OTC Price
$10/year
Estimated if OTC available
Risk Assessment
Misuse Risk
LOWMissed Diagnosis Risk
LOWRequires Monitoring
YesNeeds lab work/checkups
Lisinopril (ACE Inhibitor) Outcomes
for Chronic Kidney Disease Due To Glomerulonephritis
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+75%
Common Side Effects
Cough
+15%
Hyperkalemia
+7%
Hypotension/Dizziness
+3%
Angioedema
+0.3%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov