DFDA

ACE Inhibitors (e.g., Lisinopril)

Treatment for Chronic Kidney Disease Due To Hypertension

Typical Dosage: Lisinopril 10-40mg daily

Effectiveness
90%
Safety Score
70%
Clinical Trials
500
Participants
200K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
Lisinopril 10-40mg daily
Time to Effect
Weeks to months for full renoprotection, days for BP control
Treatment Duration
Lifetime
Evidence Quality
HIGH
Number Needed to Treat (NNT)
15(Treat 15 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
10(Treat 10 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$30
Monitoring:$1,000
Side Effect Mgmt:$75
Total Annual:$1,105
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$25,000/QALY
QALYs Gained
2
Outcome-Based Costs
Cost per Responder
$1,700
ACE Inhibitors (e.g., Lisinopril) Outcomes

for Chronic Kidney Disease Due To Hypertension

Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+65%
Common Side Effects
Cough
+10%
Hyperkalemia
+7%
Hypotension
+5%
Angioedema
+0.3%

Sources:

nih.gov
springermedizin.de
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov