Long-term Low-dose Macrolide Antibiotics (e.g., Azithromycin)

Treatment for Chronic Sinusitis

Typical Dosage: Azithromycin 250mg 3 times per week

Effectiveness
70%
Safety Score
65%
Clinical Trials
35
Participants
6K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
Azithromycin 250mg 3 times per week
Time to Effect
6-12 weeks
Treatment Duration
3-6 months
Evidence Quality
MODERATE
Number Needed to Treat (NNT)
7(Treat 7 patients to see 1 additional successful outcome)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$300
Monitoring:$150
Side Effect Mgmt:$100
Total Annual:$550
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATE
QALYs Gained
0.15
Outcome-Based Costs
Cost per Responder
$917
Cost per Remission
$5,500
Long-term Low-dose Macrolide Antibiotics (e.g., Azithromycin) Outcomes

for Chronic Sinusitis

Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+60%
Remission Rate
+10%
Common Side Effects
Gastrointestinal upset
+15%
Hearing disturbances
+3%
QTc prolongation
+1%

WARNING: LIMITED TRIALS AVAILABLE

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Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov