Lithium
Treatment for Cluster Headache
Typical Dosage: 600-1200 mg/day (titrated to serum levels)
Effectiveness
75%
Safety Score
30%
Clinical Trials
18
Participants
1.1K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
30
DangerousModerateSafe
Treatment Details
Dosage Range
600-1200 mg/day (titrated to serum levels)
Time to Effect
1-2 weeks
Treatment Duration
Months to years
Evidence Quality
MODERATENumber Needed to Treat (NNT)
6(Treat 6 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
7(Treat 7 patients to see 1 additional serious adverse event)
Confidence Score
75%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$240
Monitoring:$900
Side Effect Mgmt:$200
Total Annual:$1,340
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODQALYs Gained
0.2
Outcome-Based Costs
Cost per Responder
$2,436
Lithium Outcomes
for Cluster Headache
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+55%
Common Side Effects
Tremor
+25%
Polyuria/Polydipsia
+25%
Nausea
+15%
Weight gain
+15%
Hypothyroidism
+8%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov