DFDA

Surgical Tetralogy of Fallot (TOF) Repair

Treatment for Congenital Heart Anomalies

Effectiveness
90%
Safety Score
48%
Clinical Trials
10
Participants
100K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
48
DangerousModerateSafe
Treatment Details
Time to Effect
Immediate (defect correction), full recovery over weeks-months, long-term monitoring
Treatment Duration
Single procedure, lifetime specialized cardiac care
Evidence Quality
HIGH
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$200
Monitoring:$1,200
Side Effect Mgmt:$300
Total Annual:$1,700
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$35,000/QALY
QALYs Gained
18
Outcome-Based Costs
Cost per Responder
$1,888.89
Cost per Remission
$2,000
Surgical Tetralogy of Fallot (TOF) Repair Outcomes

for Congenital Heart Anomalies

Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+90%
Remission Rate
+85%
Common Side Effects
Pulmonary regurgitation
+20%
Residual VSD/outflow tract obstruction
+5%
Arrhythmias
+5%
Infection
+2%
Bleeding
+1%
Mortality
+2%

Sources:

nih.gov
researchgate.net
ovid.com

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
3 active trials recruiting for Surgical Tetralogy of Fallot (TOF) Repair in Congenital Heart Anomalies

Beta-blocker Administration for Cardiomyocyte Division

NCT04713657RECRUITINGPHASE1
View Study
40 participants
INTERVENTIONAL
New York, United States +2 more
Started: Dec 16, 2022

Assessment of Microvascular Circulation in the Pediatric Cardiac Surgery Patient

NCT07184476NOT YET RECRUITING
View Study
40 participants
OBSERVATIONAL
Started: Sep 29, 2025

Stress Echo 2030: the Novel ABCDE-(FGLPR) Protocol to Define the Future of Imaging

NCT05081115RECRUITING
View Study
10K participants
OBSERVATIONAL
Benevento, Italy
Started: Apr 1, 2021
Completed Clinical Trials
3 completed trials for Surgical Tetralogy of Fallot (TOF) Repair in Congenital Heart Anomalies

Effects of rhBNP in Pediatrics After Corrective Repair of Tetralogy Of Fallot

NCT01941576COMPLETEDNA
View Study
120 participants
INTERVENTIONAL
Shanghai, China
Started: Sep 1, 2013

Right Ventricular Contractility Reserve Following Repair of Tetralogy of Fallot

NCT00557934COMPLETEDNA
View Study
16 participants
INTERVENTIONAL
Tübingen, Germany
Started: Oct 1, 2007

Retrospective Review of Anesthetic Considerations for Pulmonary Artery Rehabilitation

NCT02586740COMPLETED
View Study
120 participants
OBSERVATIONAL
Columbus, United States
Started: Nov 1, 2015