DFDA

Lifestyle Modifications (Diet, Exercise, Smoking Cessation)

Treatment for Coronary Artery Disease

Typical Dosage: Exercise: 150 mins moderate intensity/week; Diet: Mediterranean/DASH; Smoking Cessation: Complete abstinence

Effectiveness
90%
Safety Score
95%
Clinical Trials
2
Participants
5M

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
95
DangerousModerateSafe
Treatment Details
Dosage Range
Exercise: 150 mins moderate intensity/week; Diet: Mediterranean/DASH; Smoking Cessation: Complete abstinence
Time to Effect
immediate for some benefits, 6-12 months for sustained cardiovascular protection
Treatment Duration
lifetime
Evidence Quality
HIGH
Number Needed to Treat (NNT)
30(Treat 30 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
100000(Treat 100000 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$300
Side Effect Mgmt:$20
Total Annual:$320
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$-5,000/QALY
QALYs Gained
0.7
Outcome-Based Costs
Cost per Responder
$1,067
Cost per Remission
$6,400
Comparison vs No Treatment
Cost Difference
$-320/year
Less expensive
QALY Difference
+0.70 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
Lifestyle Modifications (Diet, Exercise, Smoking Cessation) Outcomes

for Coronary Artery Disease

Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+30%
Remission Rate
+5%
Common Side Effects
Musculoskeletal injury (from exercise)
+5%
Nicotine withdrawal symptoms (if smoking cessation)
+30%
Difficulty adhering to dietary changes
+20%

Sources:

nih.gov
oup.com
oup.com

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
1 active trial recruiting for Lifestyle Modifications (Diet, Exercise, Smoking Cessation) in Coronary Artery Disease

Century Trial, a Randomized Lifestyle Modification Study for Management of Stable Coronary Artery Disease

NCT00756379ACTIVE NOT RECRUITINGNA
View Study
1.08K participants
INTERVENTIONAL
Houston, United States
Started: Mar 11, 2009