Dexamethasone
Treatment for Covid 19
Typical Dosage: 6 mg orally or IV once daily
Effectiveness
80%
Safety Score
50%
Clinical Trials
109
Participants
100K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
50
DangerousModerateSafe
Treatment Details
Dosage Range
6 mg orally or IV once daily
Time to Effect
2-3 days
Treatment Duration
7-10 days
Evidence Quality
HIGHNumber Needed to Treat (NNT)
25(Treat 25 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
75(Treat 75 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$20
Monitoring:$50
Side Effect Mgmt:$100
Total Annual:$170
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$1,757/QALY
QALYs Gained
0.046
Outcome-Based Costs
Cost per Responder
$485.71
Comparison vs Supportive care
Cost Difference
$-500/year
Less expensive
QALY Difference
+0.05 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
Dexamethasone Outcomes
for Covid 19
Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+35%
Common Side Effects
Hyperglycemia
+15%
Insomnia
+10%
Mood changes
+7%
Fluid retention
+8%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
12 completed trials for Dexamethasone in Covid 19
Comparison of Efficacy of Dexamethasone and Methylprednisolone in Moderate to Severe Covid 19 Disease
NCT04603729COMPLETEDPHASE3
100 participants
INTERVENTIONAL
Lahore, Pakistan
Started: May 30, 2020
C Reactive Protein in Home Quarantined Coronavirus Disease 2019 (COVID -19) Patients.
NCT04935515COMPLETEDNA
25 participants
INTERVENTIONAL
Puducherry, India
Started: Apr 15, 2021
A Simple Approach to Treat COVID-19 Patients at Home.
NCT04794998COMPLETED
180 participants
OBSERVATIONAL
Ranica, Italy
Started: Feb 8, 2021
Pirfenidone LP or Collagen-polyvinylpyrrolidone in COVID-19
NCT06585319COMPLETEDPHASE2, PHASE3
36 participants
INTERVENTIONAL
Toluca, Mexico
Started: Feb 1, 2020
Inhibition of Bradykinin in COVID-19 Infection With Icatibant
NCT05407597COMPLETEDPHASE2, PHASE3
32 participants
INTERVENTIONAL
Belfast, United Kingdom
Started: May 16, 2022
Comparing the Effects of Different Doses of Dexamethasone to Treat Inpatient COVID-19
NCT04707534COMPLETEDPHASE4
110 participants
INTERVENTIONAL
Oklahoma City, United States
Started: Jan 21, 2021
Clinical Trial to Evaluate the Efficacy of Different Treatments in Patients With COVID-19
NCT04890626COMPLETEDPHASE3
356 participants
INTERVENTIONAL
Madrid, Spain
Started: Apr 4, 2020
Effect of Two Different Doses of Dexamethasone in Patients With ARDS and COVID-19
NCT04663555COMPLETEDPHASE4
235 participants
INTERVENTIONAL
Brno, Czechia
Started: Feb 2, 2021
Randomized Clinical Trial of Intranasal Dexamethasone as an Adjuvant in Patients With COVID-19
NCT04513184COMPLETEDPHASE2
66 participants
INTERVENTIONAL
Mexico City, Mexico +2 more
Started: Nov 5, 2021
Higher vs. Lower Doses of Dexamethasone for COVID-19 and Severe Hypoxia
NCT04509973COMPLETEDPHASE3
1K participants
INTERVENTIONAL
Aalborg, Denmark +52 more
Started: Aug 27, 2020
Impact of Steroids on Inflammatory Response in Covid-19
NCT04909918COMPLETEDPHASE3
60 participants
INTERVENTIONAL
Asyut, Egypt
Started: May 28, 2021
Efficacy and Safety of Siltuximab vs. Corticosteroids in Hospitalized Patients With COVID-19 Pneumonia
NCT04329650COMPLETEDPHASE2
163 participants
INTERVENTIONAL
Badalona, Spain +3 more
Started: Apr 15, 2020
Showing 20 of 109 total trials