DFDA

Praziquantel

Treatment for Cysticercosis

Typical Dosage: 50 mg/kg/day

Effectiveness
80%
Safety Score
67%
Clinical Trials
5
Participants
8K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
67
DangerousModerateSafe
Treatment Details
Dosage Range
50 mg/kg/day
Time to Effect
1-2 months for cyst resolution
Treatment Duration
2-14 days
Evidence Quality
HIGH
Number Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
120(Treat 120 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$40
Monitoring:$1,500
Side Effect Mgmt:$200
Total Annual:$1,740
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
QALYs Gained
1.2
Outcome-Based Costs
Cost per Responder
$2,320
Cost per Remission
$2,676.9
Praziquantel Outcomes

for Cysticercosis

Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+75%
Remission Rate
+65%
Common Side Effects
Headache
+20%
Dizziness
+12%
Nausea/Vomiting
+8%
Abdominal Pain
+7%
Fever
+3%
Malaise
+3%

Sources:

neurology.org
acpjournals.org
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
2 active trials recruiting for Praziquantel in Cysticercosis

Assessment of Combined Praziquantel and Albendazole vs Albendazole Alone to Treat Active Parenchymal Neurocysticercosis

NCT06376396NOT YET RECRUITINGPHASE4
View Study
300 participants
INTERVENTIONAL
Started: Jun 1, 2024

Oxfendazole in Mild Parenchymal Brain Cysticercosis

NCT06565507NOT YET RECRUITINGPHASE2, PHASE3
View Study
544 participants
INTERVENTIONAL
Started: Dec 15, 2024
Completed Clinical Trials
2 completed trials for Praziquantel in Cysticercosis

Neurocysticercosis: Combined Treatment With Praziquantel (PZQ) and Albendazole (ABZ)

NCT00441285COMPLETEDPHASE2, PHASE3
View Study
156 participants
INTERVENTIONAL
Lima, Peru +4 more
Started: Jan 1, 2010

Taenia Solium Elimination Versus Control: What is the Best Way Forward for Sub-Saharan Africa?

NCT02612896COMPLETEDNA
View Study
2.9K participants
INTERVENTIONAL
Katete, Zambia
Started: Mar 1, 2016