Cognitive Behavioral Therapy (CBT)
Treatment for Depression
Typical Dosage: 12-20 sessions, 45-60 minutes each, weekly
Effectiveness
78%
Safety Score
95%
Clinical Trials
1,408
Participants
50K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
95
DangerousModerateSafe
Treatment Details
Dosage Range
12-20 sessions, 45-60 minutes each, weekly
Time to Effect
6-12 weeks (full course)
Treatment Duration
12-20 sessions over 3-6 months
Evidence Quality
HIGHNumber Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$2,250
Side Effect Mgmt:$0
Total Annual:$2,250
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$50,000/QALY
QALYs Gained
0.5
Outcome-Based Costs
Cost per Responder
$3,461
Cost per Remission
$4,500
Cognitive Behavioral Therapy (CBT) Outcomes
for Depression
Efficacy Outcomes
Overall Effectiveness
+78%
Response Rate
+65%
Remission Rate
+50%
Common Side Effects
Temporary emotional distress
+8%
Increased anxiety during initial sessions
+8%
Active Clinical Trials
2 active trials recruiting for Cognitive Behavioral Therapy (CBT) in Depression
Neuroimaging Markers of Midlife Depression and Cognitive Behavioural Therapy (CBT)
NCT07091643NOT YET RECRUITINGNA
30 participants
INTERVENTIONAL
Toronto, Canada
Started: Aug 1, 2025
CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth
NCT05456035RECRUITINGNA
82 participants
INTERVENTIONAL
Nashville, United States
Started: Oct 10, 2022
Completed Clinical Trials
17 completed trials for Cognitive Behavioral Therapy (CBT) in Depression
Peer Administered Online CBT for PPD
NCT04913584COMPLETEDNA
183 participants
INTERVENTIONAL
Brantford, Canada
Started: Aug 25, 2020
Online Peer-Delivered Group CBT for PPD
NCT05044455COMPLETEDNA
191 participants
INTERVENTIONAL
Hamilton, Canada
Started: Mar 28, 2022
Cognitive-Behavioral Therapy (CBT) in Women Discontinuing Antidepressant for Pregnancy
NCT01453114COMPLETEDNA
15 participants
INTERVENTIONAL
Boston, United States
Started: Nov 1, 2008
Peer Administered CBT for PPD
NCT03285139COMPLETEDNA
73 participants
INTERVENTIONAL
Brantford, Canada
Started: Jan 3, 2018
Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention
NCT04760652COMPLETEDNA
92 participants
INTERVENTIONAL
Birmingham, United States +2 more
Started: Mar 5, 2021
VA Home-Based Emotional Learning With Practical Skills
NCT01685528COMPLETEDNA
18 participants
INTERVENTIONAL
Houston, United States
Started: Dec 1, 2012
Testing Different Modes of Cognitive Behavior Therapy
NCT04279028COMPLETEDNA
22 participants
INTERVENTIONAL
Chicago, United States
Started: Feb 14, 2020
Blended Depression Therapy: Cognitive Behaviour Therapy Face-to-face and Via Internet
NCT02449447COMPLETEDNA
150 participants
INTERVENTIONAL
Linköping, Sweden
Started: Feb 1, 2015
CBT for Young Mothers
NCT03329144COMPLETEDNA
56 participants
INTERVENTIONAL
Welland, Canada
Started: Jan 3, 2018
Heart Failure Caregiver Study
NCT01937936COMPLETEDNA
50 participants
INTERVENTIONAL
Los Angeles, United States +1 more
Started: Sep 1, 2013
Brief Culturally Adapted Cognitive Behaviour Therapy for Depression
NCT01799551COMPLETEDNA
140 participants
INTERVENTIONAL
Lahore, Pakistan
Started: Nov 1, 2012
Feasibility and Effectiveness of Delivering CBT Through OPTT for Depression
NCT04478058COMPLETEDNA
110 participants
INTERVENTIONAL
Kingston, Canada
Started: Jun 1, 2019
Psilocybin-assisted CBT for Depression
NCT05227612COMPLETEDPHASE1
16 participants
INTERVENTIONAL
Los Angeles, United States
Started: Jun 27, 2023
RCT of the Clinical and Cost Effectiveness of Cognitive Behaviour Therapy (CBT) Delivered Remotely Versus Treatment as Usual in Adolescents and Young Adults With Depression Who Repeatedly Self-harm
NCT02377011COMPLETEDNA
22 participants
INTERVENTIONAL
Derby, United Kingdom +3 more
Started: Jan 1, 2014
Effects of Cognitive Behavior Therapy on Quality of Life in Paroxysmal Atrial Fibrillation Patients
NCT05893615COMPLETEDNA
102 participants
INTERVENTIONAL
Beijing, China
Started: Mar 1, 2020
Does Adding a Tailored Cognitive Behavioral Therapy (CBT) Mobile Skills App Mediate Rates of Depression
NCT04002063COMPLETEDNA
15 participants
INTERVENTIONAL
Washington D.C., United States +8 more
Started: Oct 10, 2022
Internet-based CBT After Stroke Pilot
NCT03615079COMPLETEDNA
28 participants
INTERVENTIONAL
Philadelphia, United States
Started: Jun 11, 2018
Showing 20 of 1431 total trials