Automated Insulin Delivery (AID) Systems
Treatment for Diabetes Mellitus Type 1
Typical Dosage: Automated algorithm-driven insulin delivery
Effectiveness
90%
Safety Score
55%
Clinical Trials
45
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
55
DangerousModerateSafe
Treatment Details
Dosage Range
Automated algorithm-driven insulin delivery
Time to Effect
Days-weeks for optimized control
Treatment Duration
Lifetime
Evidence Quality
HIGHConfidence Score
92%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$5,000
Monitoring:$9,000
Side Effect Mgmt:$500
Total Annual:$14,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$80,000/QALY
QALYs Gained
2
Outcome-Based Costs
Cost per Responder
$16,111
Comparison vs Multiple Daily Injections (MDI) + SMBG
Cost Difference
+$7,500/year
More expensive
QALY Difference
+0.20 QALYs
Better outcomes
Dominance
No dominance
Automated Insulin Delivery (AID) Systems Outcomes
for Diabetes Mellitus Type 1
Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+90%
Common Side Effects
Hypoglycemia
+40%
Infusion site irritation/occlusion
+15%
Diabetic Ketoacidosis (DKA)
+1%
Active Clinical Trials
10 active trials recruiting for Automated Insulin Delivery (AID) Systems in Diabetes Mellitus Type 1
NO-Meal Announcement in Automated Insulin Delivery (Open-source and Commercial) Systems
NCT07758647NOT YET RECRUITINGNA
33 participants
INTERVENTIONAL
Montreal, Canada
Started: Oct 1, 2026
Early Automated Insulin Delivery (AID) Pilot for Newly Diagnosed T1D
NCT07501338NOT YET RECRUITINGNA
16 participants
INTERVENTIONAL
Palo Alto, United States
Started: Mar 1, 2026
Commercial or Open Source Closed Loop Impact on Pregnancy Study
NCT06654713RECRUITING
1K participants
OBSERVATIONAL
San Francisco, United States
Started: Mar 13, 2025
Single Arm Intervention Trial of DEKA TWIIST TM Insulin Pump Utilizing Tidepool Loop Algorithm in Pregnant People With Pre-existing Type 1 Diabetes
NCT07808385NOT YET RECRUITINGNA
32 participants
INTERVENTIONAL
Stanford, United States +3 more
Started: Sep 1, 2026
Glycemic Control and Osteohealth in Adults Living With Type 1 Diabetes
NCT06158503RECRUITING
25 participants
OBSERVATIONAL
Montreal, Canada +1 more
Started: Feb 1, 2025
The Steno Free Trial: AID to Adults with New-onset of Type 1 Diabetes
NCT06586632NOT YET RECRUITINGNA
60 participants
INTERVENTIONAL
Started: Oct 1, 2024
Evaluation of the Safety and Effectiveness of the Novel Medtronic Experimental Automated Insulin Delivery System (NMX8) in Adults Living With Type 1 Diabetes
NCT07401901NOT YET RECRUITINGNA
230 participants
INTERVENTIONAL
Caen, France +20 more
Started: Oct 15, 2026
The diabEAT Study: Insulin dElivery Technologies And eaTing Behaviours in People With Type 1 Diabetes
NCT07348432RECRUITING
106 participants
OBSERVATIONAL
Montreal, Canada
Started: Jul 29, 2024
To Study the Efficacy and Safety of Medtronic 780G Insulin Pump in People With Gastroparesis and Type 1 Diabetes.
NCT07287943RECRUITINGNA
34 participants
INTERVENTIONAL
Indianapolis, United States
Started: Feb 9, 2026
Automated Insulin Delivery for Type 1 Diabetes - Beyond Glucose Metrics
NCT06469593RECRUITINGNA
200 participants
INTERVENTIONAL
Herlev, Denmark +2 more
Started: Jun 15, 2024
Completed Clinical Trials
10 completed trials for Automated Insulin Delivery (AID) Systems in Diabetes Mellitus Type 1
Safety and Effectiveness of Automated Insulin Delivery (AID) Systems in Physically Active Adults With Type 1 Diabetes
NCT05626725COMPLETED
76 participants
OBSERVATIONAL
Montreal, Canada
Started: Dec 1, 2022
A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes
NCT03890003COMPLETEDNA
10 participants
INTERVENTIONAL
Santa Barbara, United States
Started: Mar 28, 2019
A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes Mellitus
NCT03849612COMPLETEDNA
10 participants
INTERVENTIONAL
Walnut Creek, United States
Started: Feb 21, 2019
A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes Mellitus (T1D)
NCT03743285COMPLETEDNA
10 participants
INTERVENTIONAL
Renton, United States
Started: Nov 14, 2018
Safety and Feasibility of a Self-Learning Bolus Calculator With Simplified Meal Announcement in Adolescents With Type 1 Diabetes Using Automated Insulin Delivery
NCT07212179COMPLETEDNA
2 participants
INTERVENTIONAL
Charlottesville, United States
Started: Mar 3, 2026
A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes Mellitus During Meal Challenges
NCT03848767COMPLETEDNA
10 participants
INTERVENTIONAL
Renton, United States
Started: Feb 20, 2019
A Study of an Automated Insulin Delivery System in Participants With Type 1 Diabetes Mellitus (T1DM)
NCT03367390COMPLETEDPHASE1
30 participants
INTERVENTIONAL
Renton, United States
Started: Nov 8, 2017
Afrezza With Basal Combination (ABC): Afrezza® Combined With AID Pump or Insulin Degludec in Adults With Type 1 Diabetes
NCT05243628COMPLETEDPHASE4
33 participants
INTERVENTIONAL
Loma Linda, United States +1 more
Started: Mar 31, 2022
Automated Insulin Delivery in Pregnant Patients With Type 1 Diabetes With Extension Into Outpatient at Home
NCT04492566COMPLETEDNA
10 participants
INTERVENTIONAL
Santa Barbara, United States +2 more
Started: Jul 27, 2020
Adaptive Biobehavioral Control (ABC) of Automated Insulin Delivery
NCT04784637COMPLETEDNA
31 participants
INTERVENTIONAL
Charlottesville, United States
Started: Jul 23, 2021
Showing 20 of 61 total trials