Automated Insulin Delivery (AID) Systems
Treatment for Diabetes Mellitus Type 1
Typical Dosage: Automated algorithm-driven insulin delivery
Effectiveness
90%
Safety Score
55%
Clinical Trials
45
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
55
DangerousModerateSafe
Treatment Details
Dosage Range
Automated algorithm-driven insulin delivery
Time to Effect
Days-weeks for optimized control
Treatment Duration
Lifetime
Evidence Quality
HIGHConfidence Score
92%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$5,000
Monitoring:$9,000
Side Effect Mgmt:$500
Total Annual:$14,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$80,000/QALY
QALYs Gained
2
Outcome-Based Costs
Cost per Responder
$16,111
Comparison vs Multiple Daily Injections (MDI) + SMBG
Cost Difference
+$7,500/year
More expensive
QALY Difference
+0.20 QALYs
Better outcomes
Dominance
No dominance
Automated Insulin Delivery (AID) Systems Outcomes
for Diabetes Mellitus Type 1
Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+90%
Common Side Effects
Hypoglycemia
+40%
Infusion site irritation/occlusion
+15%
Diabetic Ketoacidosis (DKA)
+1%
Active Clinical Trials
11 active trials recruiting for Automated Insulin Delivery (AID) Systems in Diabetes Mellitus Type 1
Safety and Effectiveness of Automated Insulin Delivery (AID) Systems in Physically Active Adults with Type 1 Diabetes
NCT05626725RECRUITING
60 participants
OBSERVATIONAL
Montreal, Canada
Started: Dec 1, 2022
Safety and Feasibility of a Self-Learning Bolus Calculator With Simplified Meal Announcement in Adolescents With Type 1 Diabetes Using Automated Insulin Delivery
NCT07212179NOT YET RECRUITINGNA
6 participants
INTERVENTIONAL
Charlottesville, United States
Started: Oct 1, 2025
Commercial or Open Source Closed Loop Impact on Pregnancy Study
NCT06654713RECRUITING
1K participants
OBSERVATIONAL
San Francisco, United States
Started: Mar 13, 2025
Glycemic Control and Osteohealth in Adults Living With Type 1 Diabetes
NCT06158503RECRUITING
25 participants
OBSERVATIONAL
Montreal, Canada +1 more
Started: Feb 1, 2025
The Steno Free Trial: AID to Adults with New-onset of Type 1 Diabetes
NCT06586632NOT YET RECRUITINGNA
60 participants
INTERVENTIONAL
Started: Oct 1, 2024
Automated Insulin for Management of Intrapartum Glycemia
NCT06883344RECRUITINGNA
150 participants
INTERVENTIONAL
San Francisco, United States
Started: Dec 5, 2025
Automated Insulin Delivery for Type 1 Diabetes - Beyond Glucose Metrics
NCT06469593RECRUITINGNA
200 participants
INTERVENTIONAL
Herlev, Denmark +2 more
Started: Jun 15, 2024
Closed Loop Context Aware AID
NCT06676657RECRUITINGNA
10 participants
INTERVENTIONAL
Portland, United States
Started: Nov 22, 2024
A Fully Automated Lyumjev and Pramlintide Delivery System for Adults With Type 1 Diabetes
NCT06046417RECRUITINGPHASE2, PHASE3
30 participants
INTERVENTIONAL
Montreal, Canada
Started: Nov 30, 2023
Next Generation Advanced Insulin Delivery System in Adults With Diabetes and Advanced Renal Disease
NCT06330194ACTIVE NOT RECRUITINGNA
15 participants
INTERVENTIONAL
Copenhagen, Denmark
Started: Apr 18, 2024
To Study the Efficacy and Safety of Medtronic 780G Insulin Pump in People With Gastroparesis and Type 1 Diabetes.
NCT07287943NOT YET RECRUITINGNA
34 participants
INTERVENTIONAL
Indianapolis, United States
Started: Jan 30, 2026
Completed Clinical Trials
9 completed trials for Automated Insulin Delivery (AID) Systems in Diabetes Mellitus Type 1
A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes
NCT03890003COMPLETEDNA
10 participants
INTERVENTIONAL
Santa Barbara, United States
Started: Mar 28, 2019
A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes Mellitus
NCT03849612COMPLETEDNA
10 participants
INTERVENTIONAL
Walnut Creek, United States
Started: Feb 21, 2019
A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes Mellitus (T1D)
NCT03743285COMPLETEDNA
10 participants
INTERVENTIONAL
Renton, United States
Started: Nov 14, 2018
A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes Mellitus During Meal Challenges
NCT03848767COMPLETEDNA
10 participants
INTERVENTIONAL
Renton, United States
Started: Feb 20, 2019
A Study of an Automated Insulin Delivery System in Participants With Type 1 Diabetes Mellitus (T1DM)
NCT03367390COMPLETEDPHASE1
30 participants
INTERVENTIONAL
Renton, United States
Started: Nov 8, 2017
Afrezza With Basal Combination (ABC): Afrezza® Combined With AID Pump or Insulin Degludec in Adults With Type 1 Diabetes
NCT05243628COMPLETEDPHASE4
33 participants
INTERVENTIONAL
Loma Linda, United States +1 more
Started: Mar 31, 2022
Automated Insulin Delivery in Pregnant Patients With Type 1 Diabetes With Extension Into Outpatient at Home
NCT04492566COMPLETEDNA
10 participants
INTERVENTIONAL
Santa Barbara, United States +2 more
Started: Jul 27, 2020
Adaptive Biobehavioral Control (ABC) of Automated Insulin Delivery
NCT04784637COMPLETEDNA
31 participants
INTERVENTIONAL
Charlottesville, United States
Started: Jul 23, 2021
Automated Insulin Delivery for Inpatients With Dysglycemia
NCT06418880COMPLETEDPHASE3
130 participants
INTERVENTIONAL
Stanford, United States +2 more
Started: Jan 22, 2025
Showing 20 of 47 total trials