DFDA

Hirschsprung's Disease Pull-through Procedure

Treatment for Digestive Congenital Anomalies

Effectiveness
90%
Safety Score
48%
Clinical Trials
7
Participants
10K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
48
DangerousModerateSafe
Treatment Details
Time to Effect
Immediate surgical relief of obstruction, functional improvement over 3-6 months
Treatment Duration
Acute (surgical), 1-2 weeks hospitalization, long-term follow-up (years)
Evidence Quality
MODERATE
Confidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$500
Monitoring:$80,000
Side Effect Mgmt:$10,000
Total Annual:$90,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
QALYs Gained
68
Outcome-Based Costs
Cost per Responder
$100,556
Cost per Remission
$106,471
Hirschsprung's Disease Pull-through Procedure Outcomes

for Digestive Congenital Anomalies

Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+90%
Remission Rate
+85%
Common Side Effects
Hirschsprung-associated enterocolitis (HAEC)
+20%
Anastomotic stricture
+10%
Fecal incontinence/soiling
+20%
Constipation
+15%
Anastomotic leak
+3%

Sources:

nih.gov
researchgate.net
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
1 active trial recruiting for Hirschsprung's Disease Pull-through Procedure in Digestive Congenital Anomalies

Long-term Qualitative and Quantitative Outcomes of Children With Hirschsprung's Disease and Anorectal Malformations

NCT05450991RECRUITING
View Study
1.2K participants
OBSERVATIONAL
Liverpool, United Kingdom
Started: Jan 25, 2022
Completed Clinical Trials
3 completed trials for Hirschsprung's Disease Pull-through Procedure in Digestive Congenital Anomalies

Minimally Invasive Surgical Intervention for Hirschsprung's Disease in Pediatric Patients

NCT06874686COMPLETED
View Study
1.05K participants
OBSERVATIONAL
Hanoi, Vietnam
Started: Jan 1, 2017

Minimally Invasive Surgical Intervention for Hirschsprung Disease

NCT06880666COMPLETEDNA
View Study
23 participants
INTERVENTIONAL
Hanoi, Vietnam
Started: Jan 1, 2020

Laparoscopic-Assisted Transanal Pull-Through for Hirschsprung Disease in Pediatric:Short and Intermediate Outcomes of Two Different Techniques

NCT07186647COMPLETEDPHASE4
View Study
40 participants
INTERVENTIONAL
Cairo, Egypt
Started: Sep 1, 2020