Mineralocorticoid Receptor Antagonists (e.g., Spironolactone)
Treatment for Dilated Cardiomyopathy
Typical Dosage: Spironolactone 12.5-50mg daily
Effectiveness
85%
Safety Score
65%
Clinical Trials
1
Participants
15K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
Spironolactone 12.5-50mg daily
Time to Effect
2-6 weeks
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
18(Treat 18 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
30(Treat 30 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$30
Monitoring:$500
Side Effect Mgmt:$130
Total Annual:$660
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.7
Outcome-Based Costs
Cost per Responder
$1,100
Cost per Remission
$22,000
Mineralocorticoid Receptor Antagonists (e.g., Spironolactone) Outcomes
for Dilated Cardiomyopathy
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+60%
Remission Rate
+3%
Common Side Effects
Hyperkalemia
+15%
Gynecomastia (Spironolactone)
+10%
Hypotension
+7%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov