Penicillin G (or Procaine Penicillin)
Treatment for Diphtheria
Typical Dosage: 300,000-600,000 units IM daily or 250 mg orally QID
Effectiveness
95%
Safety Score
70%
Clinical Trials
50
Participants
15K
Comparative Safety Scale(Higher is safer)
Cyanideâ ī¸
Methđ
CigarettesđŦ
Chemoâĸī¸
Alcoholđē
Morphineđ
Antibioticsđ
Tylenolđ
Exerciseđ
Waterđ§
70
DangerousModerateSafe
Treatment Details
Dosage Range
300,000-600,000 units IM daily or 250 mg orally QID
Time to Effect
24-48 hours
Treatment Duration
14 days
Evidence Quality
HIGHNumber Needed to Harm (NNH)
10000(Treat 10000 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$20
Monitoring:$100
Side Effect Mgmt:$50
Total Annual:$170
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.3
Outcome-Based Costs
Cost per Responder
$179
Cost per Remission
$179
Prescription Access Economics
Physician Visit Cost
$125/year
Time Cost
$35/year
Travel + wait time
Insurance Admin Cost
$20/year
Prior auth, claims
Rx Price
$20/year
Potential OTC Price
$10/year
Estimated if OTC available
Early Treatment Benefit
+0.05 QALYs
From faster OTC access
Risk Assessment
Misuse Risk
MODERATEMissed Diagnosis Risk
HIGHPenicillin G (or Procaine Penicillin) Outcomes
for Diphtheria
Efficacy Outcomes
Overall Effectiveness
+95%
Response Rate
+95%
Remission Rate
+95%
Common Side Effects
Diarrhea
+8%
Nausea/Vomiting
+4%
Allergic reactions (rash)
+2%
Anaphylaxis
+0.05%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov