Artificial Tears
Treatment for Dry Eye Disease
Typical Dosage: 1-6+ drops daily as needed
Effectiveness
50%
Safety Score
90%
Clinical Trials
235
Participants
150K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
90
DangerousModerateSafe
Treatment Details
Dosage Range
1-6+ drops daily as needed
Time to Effect
immediate
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
2(Treat 2 patients to see 1 additional successful outcome)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$500
Monitoring:$100
Side Effect Mgmt:$0
Total Annual:$600
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.01
Outcome-Based Costs
Cost per Responder
$706
Cost per Remission
$30,000
Artificial Tears Outcomes
for Dry Eye Disease
Efficacy Outcomes
Overall Effectiveness
+50%
Response Rate
+85%
Remission Rate
+2%
Common Side Effects
Transient blurred vision
+1%
Mild irritation
+0.5%
Active Clinical Trials
4 active trials recruiting for Artificial Tears in Dry Eye Disease
Efficacy of Lipid-containing Artificial Tears in the Treatment of Dry Eye
NCT06955585NOT YET RECRUITINGNA
50 participants
INTERVENTIONAL
Zagreb, Croatia
Started: Apr 25, 2025
CG-101 Eye Drops in the Treatment of Dry Eye Syndrome
NCT06792903RECRUITINGEARLY_PHASE1
30 participants
INTERVENTIONAL
Shanghai, China
Started: Apr 23, 2024
Comparative Efficacy of Lipid Based Artificial Tears vs Aqueous Based Artificial Tears in Managing EDE
NCT06913387ACTIVE NOT RECRUITINGNA
60 participants
INTERVENTIONAL
Lahore, Pakistan
Started: Mar 20, 2025
Evaluating the Efficacy of Topical Insulin for the Restoration of Ocular Surface Interface in Dry Eye Disease.
NCT06939959RECRUITINGPHASE4
126 participants
INTERVENTIONAL
Peshawar, Pakistan
Started: Apr 14, 2025
Completed Clinical Trials
11 completed trials for Artificial Tears in Dry Eye Disease
Tear Osmolarity Changes After Instilling Isotonic Hyaluronate Artificial Tears
NCT01614847COMPLETEDPHASE4
8 participants
INTERVENTIONAL
Tahlequah, United States
Started: Jun 1, 2012
Hydroxypropyl-methylcellulose and GlicoPro® Eyedrops in the Treatment of Dry Eye Disease: Clinical Study
NCT06726525COMPLETEDPHASE4
44 participants
INTERVENTIONAL
Messina, Italy
Started: Feb 3, 2024
Efficacy of Pilocarpine As a Secretagogue Versus Artificial Tears for the Treatment of Dry Eye
NCT06752278COMPLETEDNA
40 participants
INTERVENTIONAL
Damietta, Egypt
Started: Oct 1, 2024
A Study to Investigate the Effect of 0.003% AR-15512 on Subjects With Dry Eye Disease
NCT06544694COMPLETEDPHASE3
79 participants
INTERVENTIONAL
Louisville, United States +3 more
Started: Oct 8, 2024
Safety and Tolerability of the Ophthalmic Gel PRO-165 Versus Artelac® Nightime Gel
NCT03697876COMPLETEDPHASE1
32 participants
INTERVENTIONAL
Mexico City, Mexico
Started: Aug 20, 2018
Study on Curative Effect and Mechanism of Acupuncture on Neuropathic Pain in Dry Eye Disease
NCT04668131COMPLETEDNA
20 participants
INTERVENTIONAL
Beijing, China +1 more
Started: Sep 22, 2020
A Natural History Study of Patients With Dry Eye
NCT00833235COMPLETED
284 participants
OBSERVATIONAL
Little Rock, United States +16 more
Started: Feb 1, 2009
Study on Safety and Performance of an Artificial Tear in Dry Eye Treatment in Subjects With Ocular Surface Inflammation
NCT04633863COMPLETEDNA
24 participants
INTERVENTIONAL
Lucca, Italy
Started: Oct 12, 2020
The Visual Effect of an Investigational Artificial Tear in the Tear Layer.
NCT00395759COMPLETEDNA
30 participants
INTERVENTIONAL
Fullerton, United States
Started: Sep 1, 2005
Safety and Efficacy of Licaminlimab Ophthalmic Solution for the Treatment of Dry Eye Disease
NCT05896670COMPLETEDPHASE2
122 participants
INTERVENTIONAL
Newport Beach, United States +4 more
Started: Nov 29, 2023
Efficacy and Safety of Fluorometholone (FML) in Dry Eye Disease (Keratoconjunctivitis Sicca)
NCT02051023COMPLETEDPHASE3
41 participants
INTERVENTIONAL
Valladolid, Spain +1 more
Started: Feb 1, 2014
Showing 20 of 239 total trials