Loteprednol etabonate ophthalmic suspension (short-term)
Treatment for Dry Eye Disease
Typical Dosage: One drop 2-4 times daily, then taper
Effectiveness
75%
Safety Score
65%
Clinical Trials
60
Participants
9K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
One drop 2-4 times daily, then taper
Time to Effect
Days to 1 week
Treatment Duration
2-4 weeks (pulsed therapy)
Evidence Quality
HIGHNumber Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$250
Monitoring:$50
Side Effect Mgmt:$20
Total Annual:$320
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODQALYs Gained
0.02
Outcome-Based Costs
Cost per Responder
$427
Loteprednol etabonate ophthalmic suspension (short-term) Outcomes
for Dry Eye Disease
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+75%
Common Side Effects
Ocular pain/stinging
+10%
Blurred vision
+5%
Transient increase in IOP (low risk with short-term use)
+1%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov