DFDA

Omega-3 Fatty Acids (EPA/DHA)

Treatment for Dry Eye Disease

Typical Dosage: 1000-2000mg EPA+DHA daily

Effectiveness
60%
Safety Score
85%
Clinical Trials
9
Participants
12K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
85
DangerousModerateSafe
Treatment Details
Dosage Range
1000-2000mg EPA+DHA daily
Time to Effect
1-3 months
Treatment Duration
lifetime
Evidence Quality
MODERATE
Number Needed to Treat (NNT)
9(Treat 9 patients to see 1 additional successful outcome)
Confidence Score
70%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$400
Monitoring:$500
Side Effect Mgmt:$0
Total Annual:$900
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
POOR
QALYs Gained
0.01
Outcome-Based Costs
Cost per Responder
$1,000
Cost per Remission
$8,000
Comparison vs Artificial Tears
Cost Difference
$-200/year
Less expensive
QALY Difference
-0.01 QALYs
Worse outcomes
Dominance
No dominance
Omega-3 Fatty Acids (EPA/DHA) Outcomes

for Dry Eye Disease

Efficacy Outcomes
Overall Effectiveness
+60%
Response Rate
+40%
Remission Rate
+5%
Common Side Effects
Fishy aftertaste
+10%
Gastrointestinal upset
+5%

Sources:

nih.gov
researchgate.net
researchgate.net

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
1 active trial recruiting for Omega-3 Fatty Acids (EPA/DHA) in Dry Eye Disease

Efficacy of OmegaBoost to Increase Omega-3 Levels in Healthy Individuals

NCT05763940ACTIVE NOT RECRUITINGNA
View Study
130 participants
INTERVENTIONAL
Pomona, United States
Started: May 25, 2022
Completed Clinical Trials
4 completed trials for Omega-3 Fatty Acids (EPA/DHA) in Dry Eye Disease

Dry Eye Assessment and Management: Feasibility Study

NCT01102257COMPLETEDPHASE2, PHASE3
View Study
23 participants
INTERVENTIONAL
New York, United States
Started: Jan 1, 2010

Dry Eye Assessment and Management Study

NCT02128763COMPLETEDPHASE3
View Study
535 participants
INTERVENTIONAL
Scottsdale, United States +26 more
Started: Nov 1, 2014

A Placebo Controlled Double Masked Clinical Assessment Study of Essential Fatty Acid Supplement and Its Effect on Patients With Apparent Aqueous Deficient Dry Eye Syndrome

NCT00344721COMPLETEDNA
View Study
42 participants
INTERVENTIONAL
Dallas, United States
Started: Sep 1, 2004

The Effects of Dietary Supplementation With Omega-3 Fatty Acids on Symptoms of Dry Eye

NCT03141931COMPLETEDNA
View Study
119 participants
INTERVENTIONAL
Sydney, Australia
Started: Aug 21, 2017