Punctal Plugs (Silicone or dissolvable)
Treatment for Dry Eye Disease
Typical Dosage: 1-4 plugs per patient
Effectiveness
70%
Safety Score
85%
Clinical Trials
25
Participants
3.5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
85
DangerousModerateSafe
Treatment Details
Dosage Range
1-4 plugs per patient
Time to Effect
immediate
Treatment Duration
temporary (dissolvable) or permanent (silicone)
Evidence Quality
MODERATENumber Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$300
Side Effect Mgmt:$100
Total Annual:$500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$25,000/QALY
QALYs Gained
0.05
Outcome-Based Costs
Cost per Responder
$833
Cost per Remission
$3,333
Comparison vs Artificial Tears
Cost Difference
$-100/year
Less expensive
QALY Difference
+0.04 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
Punctal Plugs (Silicone or dissolvable) Outcomes
for Dry Eye Disease
Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+60%
Remission Rate
+15%
Common Side Effects
Foreign body sensation
+10%
Epiphora (excessive tearing)
+5%
Plug extrusion
+15%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov