Fluticasone/Salmeterol (ICS/LABA combination)
Treatment for Emphysema
Typical Dosage: Fluticasone propionate 250 mcg / salmeterol 50 mcg, twice daily
Effectiveness
65%
Safety Score
60%
Clinical Trials
80
Participants
40K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
Fluticasone propionate 250 mcg / salmeterol 50 mcg, twice daily
Time to Effect
within 10-20 minutes for bronchodilation, weeks for anti-inflammatory effects
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
11(Treat 11 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
40(Treat 40 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$6,000
Monitoring:$800
Side Effect Mgmt:$100
Total Annual:$6,900
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEICER
$100,000/QALY
QALYs Gained
0.15
Outcome-Based Costs
Cost per Responder
$12,545
Fluticasone/Salmeterol (ICS/LABA combination) Outcomes
for Emphysema
Efficacy Outcomes
Overall Effectiveness
+65%
Response Rate
+55%
Common Side Effects
Oral candidiasis (thrush)
+7%
Upper respiratory tract infection
+9%
Headache
+7.5%
Pneumonia
+4%
Pharyngitis
+6.5%
Bronchitis
+5.5%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov