Tiotropium (LAMA)
Treatment for Emphysema
Typical Dosage: 18 mcg once daily
Effectiveness
70%
Safety Score
65%
Clinical Trials
1
Participants
50K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
18 mcg once daily
Time to Effect
within 30 minutes
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
12(Treat 12 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
7(Treat 7 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$5,000
Monitoring:$800
Side Effect Mgmt:$100
Total Annual:$5,900
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$50,000/QALY
QALYs Gained
0.2
Outcome-Based Costs
Cost per Responder
$9,077
Tiotropium (LAMA) Outcomes
for Emphysema
Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+65%
Common Side Effects
Dry mouth
+15%
Upper respiratory tract infection
+4.5%
Pharyngitis
+2%
Sinusitis
+1.5%
Urinary tract infection
+1.5%
Dyspepsia
+1.5%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
1 completed trial for Tiotropium (LAMA) in Emphysema
A 1-year Multi-center, Prospective, Cohort Study in Patients With Chronic Obstructive Pulmonary Disease Treated With Long-acting Bronchodilator
NCT01794780COMPLETEDPHASE4
2.23K participants
INTERVENTIONAL
Beijing, China +1 more
Started: Feb 5, 2013