Acyclovir
Treatment for Encephalitis
Typical Dosage: 10 mg/kg IV every 8 hours
Effectiveness
90%
Safety Score
70%
Clinical Trials
4
Participants
5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
10 mg/kg IV every 8 hours
Time to Effect
Days
Treatment Duration
14-21 days intravenously
Evidence Quality
HIGHNumber Needed to Treat (NNT)
2(Treat 2 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
50(Treat 50 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$500
Monitoring:$10,000
Side Effect Mgmt:$500
Total Annual:$11,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$25,000/QALY
QALYs Gained
8
Outcome-Based Costs
Cost per Responder
$15,714
Cost per Remission
$36,667
Acyclovir Outcomes
for Encephalitis
Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+70%
Remission Rate
+30%
Common Side Effects
Nausea
+3%
Headache
+3%
Renal impairment
+2%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
2 completed trials for Acyclovir in Encephalitis
Impact of Obesity on Clinical Outcomes in Patients Receiving Acyclovir for HSV Encephalitis"
NCT05127395COMPLETED
50 participants
OBSERVATIONAL
Dallas, United States
Started: Mar 9, 2021
Long Term Treatment of Herpes Simplex Encephalitis (HSE) With Valacyclovir
NCT00031486COMPLETEDPHASE3
91 participants
INTERVENTIONAL
Birmingham, United States +20 more
Started: Sep 1, 2000