Plasma Exchange (PLEX)
Treatment for Encephalitis
Typical Dosage: 1-1.5 plasma volumes exchanged per session
Effectiveness
80%
Safety Score
50%
Clinical Trials
70
Participants
2K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
50
DangerousModerateSafe
Treatment Details
Dosage Range
1-1.5 plasma volumes exchanged per session
Time to Effect
5-10 days
Treatment Duration
5-7 exchanges over 1-2 weeks
Evidence Quality
MODERATENumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
10(Treat 10 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$35,000
Side Effect Mgmt:$1,500
Total Annual:$36,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEICER
$110,000/QALY
QALYs Gained
7
Outcome-Based Costs
Cost per Responder
$60,833
Cost per Remission
$81,111
Plasma Exchange (PLEX) Outcomes
for Encephalitis
Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+60%
Remission Rate
+45%
Common Side Effects
Hypotension
+15%
Citrate toxicity
+10%
Catheter-related infection
+2%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov