DFDA

Ceftriaxone

Treatment for Endocarditis

Typical Dosage: 2g IV once daily

Effectiveness
90%
Safety Score
70%
Clinical Trials
4
Participants
8K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
2g IV once daily
Time to Effect
3-6 days
Treatment Duration
2-6 weeks IV
Evidence Quality
HIGH
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$900
Monitoring:$105,000
Side Effect Mgmt:$1,500
Total Annual:$107,400
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
QALYs Gained
1.3
Outcome-Based Costs
Cost per Responder
$126,353
Cost per Remission
$137,692
Ceftriaxone Outcomes

for Endocarditis

Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+85%
Remission Rate
+78%
Common Side Effects
Diarrhea/GI upset
+7%
Rash/Hypersensitivity
+3%
Gallbladder sludge/pseudolithiasis
+1.5%
Increased LFTs
+3%

Sources:

nih.gov
researchgate.net
mdpi.com

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
1 active trial recruiting for Ceftriaxone in Endocarditis

Ampicillin and Ceftriaxone for the Treatment of Enterococcus Faecalis Infective Endocarditis.

NCT06423898RECRUITINGPHASE4
View Study
284 participants
INTERVENTIONAL
Alava, Spain +17 more
Started: Oct 9, 2024
Completed Clinical Trials
1 completed trial for Ceftriaxone in Endocarditis

Evaluation of an Antibiotic Regimen Pharmacokinetic Applicable to Enterococcus Faecalis Infective Endocarditis

NCT03681431COMPLETEDPHASE2
View Study
12 participants
INTERVENTIONAL
Seville, Spain
Started: Apr 23, 2018