Vancomycin + Gentamicin
Treatment for Endocarditis
Typical Dosage: Vancomycin 15-20 mg/kg IV q8-12h; Gentamicin 1 mg/kg IV q8h or 3 mg/kg once daily
Effectiveness
87%
Safety Score
65%
Clinical Trials
2
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
Vancomycin 15-20 mg/kg IV q8-12h; Gentamicin 1 mg/kg IV q8h or 3 mg/kg once daily
Time to Effect
3-7 days
Treatment Duration
4-6 weeks IV
Evidence Quality
HIGHConfidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$1,250
Monitoring:$122,500
Side Effect Mgmt:$6,000
Total Annual:$129,750
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEQALYs Gained
0.9
Outcome-Based Costs
Cost per Responder
$166,346
Cost per Remission
$190,809
Vancomycin + Gentamicin Outcomes
for Endocarditis
Efficacy Outcomes
Overall Effectiveness
+87%
Response Rate
+78%
Remission Rate
+68%
Common Side Effects
Nephrotoxicity
+12%
Ototoxicity (Gentamicin)
+3%
Red Man Syndrome (Vancomycin)
+7%
Nausea/Vomiting
+7%
Rash/Hypersensitivity
+3.5%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov