Systemic Chemotherapy (e.g., FOLFOX/CAPOX)
Treatment for Esophageal Cancer
Typical Dosage: e.g., FOLFOX: Oxaliplatin 85 mg/m2, Leucovorin 400 mg/m2, 5-FU 400 mg/m2 bolus then 2400 mg/m2 over 46 hours every 2 weeks.
Effectiveness
70%
Safety Score
25%
Clinical Trials
3,000
Participants
50K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
25
DangerousModerateSafe
Treatment Details
Dosage Range
e.g., FOLFOX: Oxaliplatin 85 mg/m2, Leucovorin 400 mg/m2, 5-FU 400 mg/m2 bolus then 2400 mg/m2 over 46 hours every 2 weeks.
Time to Effect
1-2 months
Treatment Duration
multiple cycles, until progression or toxicity
Evidence Quality
HIGHNumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$40,000
Monitoring:$15,000
Side Effect Mgmt:$10,000
Total Annual:$65,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$70,000/QALY
QALYs Gained
0.5
Outcome-Based Costs
Cost per Responder
$162,500
Cost per Remission
$1,300,000
Systemic Chemotherapy (e.g., FOLFOX/CAPOX) Outcomes
for Esophageal Cancer
Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+40%
Remission Rate
+5%
Common Side Effects
Nausea/Vomiting
+70%
Myelosuppression (Neutropenia)
+50%
Fatigue
+80%
Peripheral Neuropathy
+25%
Mucositis
+40%
Hair Loss
+60%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov