Delamanid (as part of longer regimens)
Treatment for Extensively Drug Resistant Tuberculosis
Typical Dosage: 100mg twice daily for 24 weeks
Effectiveness
78%
Safety Score
50%
Clinical Trials
15
Participants
2.5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
50
DangerousModerateSafe
Treatment Details
Dosage Range
100mg twice daily for 24 weeks
Time to Effect
3-6 months
Treatment Duration
6 months (within 18-24 month regimen)
Evidence Quality
HIGHConfidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$5,000
Monitoring:$2,000
Side Effect Mgmt:$1,000
Total Annual:$8,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$25,000/QALY
QALYs Gained
1.1
Outcome-Based Costs
Cost per Responder
$10,667
Cost per Remission
$10,667
Comparison vs Older XDR-TB regimens without Delamanid
Cost Difference
$-4,000/year
Less expensive
QALY Difference
+0.70 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
Delamanid (as part of longer regimens) Outcomes
for Extensively Drug Resistant Tuberculosis
Efficacy Outcomes
Overall Effectiveness
+78%
Response Rate
+75%
Remission Rate
+75%
Common Side Effects
QT prolongation
+15%
Nausea/Vomiting
+20%
Headache
+12%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov