DFDA

Vaginal Pessaries

Treatment for Genital Prolapse

Typical Dosage: Various sizes and types, fitted by clinician

Effectiveness
75%
Safety Score
85%
Clinical Trials
7
Participants
10K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
85
DangerousModerateSafe
Treatment Details
Dosage Range
Various sizes and types, fitted by clinician
Time to Effect
Immediate symptom relief once fitted
Treatment Duration
Long-term, often lifelong
Evidence Quality
HIGH
Number Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$600
Side Effect Mgmt:$100
Total Annual:$700
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
QALYs Gained
0.4
Outcome-Based Costs
Cost per Responder
$875
Comparison vs Surgical Repair
Cost Difference
$-12,300/year
Less expensive
QALY Difference
-0.10 QALYs
Worse outcomes
Dominance
No dominance
Prescription Access Economics
Physician Visit Cost
$360/year
Time Cost
$180/year
Travel + wait time
Insurance Admin Cost
$50/year
Prior auth, claims
Rx Price
$75/year
Risk Assessment
Misuse Risk
MODERATE
Missed Diagnosis Risk
LOW
Requires Monitoring
Yes
Needs lab work/checkups
Vaginal Pessaries Outcomes

for Genital Prolapse

Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+80%
Common Side Effects
Vaginal discharge
+40%
Vaginal irritation/erosion
+15%
Vaginal infection
+8%
Odor
+15%
Pain/discomfort
+10%

Sources:

obgproject.com
nih.gov
researchgate.net

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
3 active trials recruiting for Vaginal Pessaries in Genital Prolapse

Prospective Observational Prolapse Study

NCT04701047RECRUITING
View Study
200 participants
OBSERVATIONAL
Ghent, Belgium
Started: Sep 3, 2021

Perineal Massage for Pessary Examinations

NCT06416982ACTIVE NOT RECRUITINGNA
View Study
68 participants
INTERVENTIONAL
Raleigh, United States
Started: Aug 1, 2024

Treatment of Vaginal Atrophy With Low Intensity Nanosecond Neodymium Laser

NCT05335317RECRUITINGNA
View Study
120 participants
INTERVENTIONAL
Nizhny Novgorod, Russia
Started: Apr 18, 2022
Completed Clinical Trials
2 completed trials for Vaginal Pessaries in Genital Prolapse

Cross-Shaped Vaginal Pessary for Pelvic Organ Prolapse

NCT07554651COMPLETEDNA
View Study
51 participants
INTERVENTIONAL
Dnipro, Ukraine +4 more
Started: Sep 1, 2024

Vaginal Estrogen With Pessary Treatment

NCT01843166COMPLETEDNA
View Study
150 participants
INTERVENTIONAL
London, Canada
Started: Jul 1, 2012