DFDA

Chlorhexidine Gluconate Mouthrinse (0.12%)

Treatment for Gingivitis

Typical Dosage: 15mL, rinse twice daily for 30-60 seconds

Effectiveness
85%
Safety Score
75%
Clinical Trials
4
Participants
30K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
75
DangerousModerateSafe
Treatment Details
Dosage Range
15mL, rinse twice daily for 30-60 seconds
Time to Effect
1-2 weeks
Treatment Duration
2-4 weeks (short-term/intermittent)
Evidence Quality
HIGH
Number Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$120
Monitoring:$500
Side Effect Mgmt:$0
Total Annual:$620
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
QALYs Gained
0.08
Outcome-Based Costs
Cost per Responder
$150
Cost per Remission
$200
Comparison vs Daily Mechanical Plaque Removal Alone
Cost Difference
+$120/year
More expensive
QALY Difference
+0.08 QALYs
Better outcomes
Dominance
No dominance
Prescription Access EconomicsOTC Available
Physician Visit Cost
$0/year
Time Cost
$0/year
Travel + wait time
Rx Price
$120/year
Potential OTC Price
$100/year
Estimated if OTC available
Risk Assessment
Misuse Risk
LOW
Missed Diagnosis Risk
LOW
Chlorhexidine Gluconate Mouthrinse (0.12%) Outcomes

for Gingivitis

Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+80%
Remission Rate
+60%
Common Side Effects
Tooth/tongue staining
+40%
Taste alteration
+20%
Increased calculus formation
+10%

Sources:

wikipedia.org
todaysrdh.com
ijpi.in

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
No active trials currently recruiting for this treatment

No active trials found in ClinicalTrials.gov

Completed Clinical Trials
3 completed trials for Chlorhexidine Gluconate Mouthrinse (0.12%) in Gingivitis

Comparative Evaluation of Antiplaque and Antigingivitis Efficacy of Ocimum Sanctum (Tulsi) Extract

NCT03474146COMPLETEDNA
View Study
90 participants
INTERVENTIONAL
Indore, India
Started: Apr 12, 2017

SmartMouth Advanced Clinical Formula Clinical Research Design Protocol

NCT02709785COMPLETEDNA
View Study
80 participants
INTERVENTIONAL
Alton, United States +1 more
Started: Mar 1, 2016

Clinical Effects of Two New Chlorhexidine Digluconate Formulations: 0.12% and 0.03%.

NCT02194023COMPLETEDPHASE2
View Study
200 participants
INTERVENTIONAL
Sant Cugat del Vallès, Spain
Started: Sep 1, 2011