ACE Inhibitors (Lisinopril) / ARBs (Valsartan)
Treatment for Heart Failure
Typical Dosage: Lisinopril 2.5-5 mg daily up to 20-40 mg daily; Valsartan 20-40 mg BID up to 160 mg BID
Effectiveness
78%
Safety Score
70%
Clinical Trials
100
Participants
50K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
Lisinopril 2.5-5 mg daily up to 20-40 mg daily; Valsartan 20-40 mg BID up to 160 mg BID
Time to Effect
1-3 months
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
25(Treat 25 patients to see 1 additional successful outcome)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$150
Monitoring:$600
Side Effect Mgmt:$75
Total Annual:$825
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$5,000/QALY
QALYs Gained
0.9
Outcome-Based Costs
Cost per Responder
$1,833
Comparison vs No treatment
Cost Difference
$-1,200/year
Less expensive
QALY Difference
+0.90 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
ACE Inhibitors (Lisinopril) / ARBs (Valsartan) Outcomes
for Heart Failure
Efficacy Outcomes
Overall Effectiveness
+78%
Response Rate
+45%
Common Side Effects
Cough
+12%
Hypotension
+8%
Dizziness
+8%
Hyperkalemia
+4%
Angioedema
+0.2%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov