Rubber Band Ligation
Treatment for Hemorrhoids
Typical Dosage: 1-2 bands per session
Effectiveness
83%
Safety Score
65%
Clinical Trials
14
Participants
55K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
1-2 bands per session
Time to Effect
Days to 1 week
Treatment Duration
Multiple sessions (1-3) over several weeks
Evidence Quality
HIGHConfidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$50
Monitoring:$450
Side Effect Mgmt:$150
Total Annual:$2,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$6,667/QALY
QALYs Gained
0.3
Outcome-Based Costs
Cost per Responder
$2,667
Cost per Remission
$3,077
Rubber Band Ligation Outcomes
for Hemorrhoids
Efficacy Outcomes
Overall Effectiveness
+83%
Response Rate
+75%
Remission Rate
+65%
Common Side Effects
Pain/Discomfort
+40%
Bleeding
+7%
Vasovagal syncope
+1%
Sources:
Active Clinical Trials
5 active trials recruiting for Rubber Band Ligation in Hemorrhoids
Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS
NCT07559630RECRUITINGNA
40 participants
INTERVENTIONAL
Los Angeles, United States
Started: May 19, 2026
Endoscopic Rubber Band Ligation and Milligan-Morgan Hemorrhoidectomy for the Treatment of Grade II-III Internal Hemorrhoids: a Multicenter, Non-randomized Controlled Study
NCT06794151ACTIVE NOT RECRUITING
548 participants
OBSERVATIONAL
China, China
Started: Jan 1, 2025
Evaluation of Superior Rectal Arterial Embolization in Hemorrhoidal Disease
NCT05697562RECRUITINGNA
80 participants
INTERVENTIONAL
Jette, Belgium
Started: Jun 1, 2023
Nitroglycerin Ointment for Pain Relief After Endoscopic Hemorrhoid Band Ligation
NCT07391501NOT YET RECRUITINGPHASE4
68 participants
INTERVENTIONAL
Started: Feb 1, 2026
Argon Plasma Coagulation in Open Excisional Hemorrhoidectomy
NCT07587892ACTIVE NOT RECRUITINGNA
100 participants
INTERVENTIONAL
Moscow, Russia
Started: Aug 1, 2023
Completed Clinical Trials
5 completed trials for Rubber Band Ligation in Hemorrhoids
Comparison of Outcome of Injection Sclerotherapy Versus Rubber Band Ligation for Second Degree Hemorrhoids
NCT07199673COMPLETEDNA
128 participants
INTERVENTIONAL
Lahore, Pakistan
Started: Jul 7, 2025
Comparison Between Two Endoscopic Treatments of Bleeding Internal Hemorrhoids:Band Ligation and Electrocoagulation Probe
NCT00630669COMPLETEDNA
45 participants
INTERVENTIONAL
Los Angeles, United States
Started: Dec 1, 1997
Polidocanol Foam Versus Rubber Band Ligation in the Treatment of Hemorrhoidal Disease
NCT04091763COMPLETEDPHASE2
120 participants
INTERVENTIONAL
Porto, Portugal
Started: Aug 1, 2018
The Effect of Rubber Band Ligation in Bleeding Internal Hemorrhoids.
NCT04290351COMPLETED
69 participants
OBSERVATIONAL
Konya, Turkey (Türkiye)
Started: Nov 1, 2020
Topical Anesthesia Versus Placebo to Decrease Pain in Rubber Band Ligation for Treatment of Internal Hemorrhoids
NCT02130830COMPLETEDPHASE3
80 participants
INTERVENTIONAL
Santiago, Chile
Started: May 1, 2014