Sclerotherapy
Treatment for Hemorrhoids
Typical Dosage: 3-5ml sclerosant per hemorrhoid
Effectiveness
72%
Safety Score
65%
Clinical Trials
14
Participants
40K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
3-5ml sclerosant per hemorrhoid
Time to Effect
Days to 1 week
Treatment Duration
Multiple sessions (1-4) over several weeks
Evidence Quality
MODERATEConfidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$350
Side Effect Mgmt:$75
Total Annual:$1,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$7,500/QALY
QALYs Gained
0.2
Outcome-Based Costs
Cost per Responder
$2,308
Cost per Remission
$3,333
Sclerotherapy Outcomes
for Hemorrhoids
Efficacy Outcomes
Overall Effectiveness
+72%
Response Rate
+65%
Remission Rate
+45%
Common Side Effects
Mild discomfort/pain
+15%
Bleeding
+3%
Rectal ulceration
+0.5%
Sources:
Active Clinical Trials
2 active trials recruiting for Sclerotherapy in Hemorrhoids
CAES for Internal Hemorrhoids and Rectal Prolapse
NCT04169152RECRUITING
10K participants
OBSERVATIONAL
Nanjing, China
Started: Dec 30, 2019
Argon Plasma Coagulation in Open Excisional Hemorrhoidectomy
NCT07587892ACTIVE NOT RECRUITINGNA
100 participants
INTERVENTIONAL
Moscow, Russia
Started: Aug 1, 2023
Completed Clinical Trials
5 completed trials for Sclerotherapy in Hemorrhoids
Comparison of Outcome of Injection Sclerotherapy Versus Rubber Band Ligation for Second Degree Hemorrhoids
NCT07199673COMPLETEDNA
128 participants
INTERVENTIONAL
Lahore, Pakistan
Started: Jul 7, 2025
Endoscopic Injection Sclerotherapy Versus Endoscopic Band Ligation for Grade I-III Internal Hemorrhoids
NCT05089500COMPLETEDNA
984 participants
INTERVENTIONAL
Wuhan, China +1 more
Started: Nov 1, 2021
Polidocanol Foam VS Artery Ligation in Hemorrhoidal Disease
NCT04675177COMPLETEDPHASE2, PHASE3
45 participants
INTERVENTIONAL
Porto, Portugal
Started: Sep 1, 2019
Polidocanol Foam Versus Rubber Band Ligation in the Treatment of Hemorrhoidal Disease
NCT04091763COMPLETEDPHASE2
120 participants
INTERVENTIONAL
Porto, Portugal
Started: Aug 1, 2018
Efficacy and Safety of Polidocanol Foam 3% in the Treatment of II Degree Hemorrhoidal Disease
NCT03791775COMPLETEDPHASE2
183 participants
INTERVENTIONAL
Catanzaro, Italy
Started: Jan 2, 2019