DFDA

Sclerotherapy

Treatment for Hemorrhoids

Typical Dosage: 3-5ml sclerosant per hemorrhoid

Effectiveness
72%
Safety Score
65%
Clinical Trials
14
Participants
40K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
3-5ml sclerosant per hemorrhoid
Time to Effect
Days to 1 week
Treatment Duration
Multiple sessions (1-4) over several weeks
Evidence Quality
MODERATE
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$350
Side Effect Mgmt:$75
Total Annual:$1,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENT
ICER
$7,500/QALY
QALYs Gained
0.2
Outcome-Based Costs
Cost per Responder
$2,308
Cost per Remission
$3,333
Sclerotherapy Outcomes

for Hemorrhoids

Efficacy Outcomes
Overall Effectiveness
+72%
Response Rate
+65%
Remission Rate
+45%
Common Side Effects
Mild discomfort/pain
+15%
Bleeding
+3%
Rectal ulceration
+0.5%

Sources:

nih.gov
researchgate.net
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
3 active trials recruiting for Sclerotherapy in Hemorrhoids

Comparison of Outcome of Injection Sclerotherapy Versus Rubber Band Ligation for Second Degree Hemorrhoids

NCT07199673ACTIVE NOT RECRUITINGNA
View Study
128 participants
INTERVENTIONAL
Lahore, Pakistan
Started: Jul 7, 2025

CAES for Internal Hemorrhoids and Rectal Prolapse

NCT04169152RECRUITING
View Study
10K participants
OBSERVATIONAL
Nanjing, China
Started: Dec 30, 2019

Cap-assisted Endoscopic Sclerotherapy for Internal Hemorrhoids and Rectal Prolapse

NCT03917056RECRUITINGNA
View Study
1K participants
INTERVENTIONAL
Nanjing, China
Started: Jun 24, 2019
Completed Clinical Trials
3 completed trials for Sclerotherapy in Hemorrhoids

Polidocanol Foam VS Artery Ligation in Hemorrhoidal Disease

NCT04675177COMPLETEDPHASE2, PHASE3
View Study
45 participants
INTERVENTIONAL
Porto, Portugal
Started: Sep 1, 2019

Polidocanol Foam Versus Rubber Band Ligation in the Treatment of Hemorrhoidal Disease

NCT04091763COMPLETEDPHASE2
View Study
120 participants
INTERVENTIONAL
Porto, Portugal
Started: Aug 1, 2018

Efficacy and Safety of Polidocanol Foam 3% in the Treatment of II Degree Hemorrhoidal Disease

NCT03791775COMPLETEDPHASE2
View Study
183 participants
INTERVENTIONAL
Catanzaro, Italy
Started: Jan 2, 2019