ABVD (Doxorubicin, Bleomycin, Vinblastine, Dacarbazine)
Treatment for Hodgkin Lymphoma
Typical Dosage: Standardized regimen (e.g., Doxorubicin 25mg/m2, Bleomycin 10mg/m2, Vinblastine 6mg/m2, Dacarbazine 375mg/m2, on days 1 & 15 of 28-day cycles)
Effectiveness
85%
Safety Score
25%
Clinical Trials
48
Participants
75K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
25
DangerousModerateSafe
Treatment Details
Dosage Range
Standardized regimen (e.g., Doxorubicin 25mg/m2, Bleomycin 10mg/m2, Vinblastine 6mg/m2, Dacarbazine 375mg/m2, on days 1 & 15 of 28-day cycles)
Time to Effect
Weeks to months
Treatment Duration
4-6 months
Evidence Quality
HIGHConfidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$12,000
Monitoring:$10,000
Side Effect Mgmt:$7,500
Total Annual:$29,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
25
Outcome-Based Costs
Cost per Responder
$34,706
Cost per Remission
$39,333
ABVD (Doxorubicin, Bleomycin, Vinblastine, Dacarbazine) Outcomes
for Hodgkin Lymphoma
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+85%
Remission Rate
+75%
Common Side Effects
Nausea/Vomiting
+80%
Hair Loss
+100%
Fatigue
+75%
Neutropenia
+60%
Bleomycin-induced Lung Toxicity
+10%
Cardiotoxicity (Doxorubicin)
+5%
Active Clinical Trials
3 active trials recruiting for ABVD (Doxorubicin, Bleomycin, Vinblastine, Dacarbazine) in Hodgkin Lymphoma
First Line Chemotherapy for Classical Hodgkin Lymphoma in Russia (HL-Russia-1)
NCT04638790RECRUITINGPHASE3
300 participants
INTERVENTIONAL
Mumbai, India +1 more
Started: Feb 1, 2020
A Frontline Therapy Trial in Participants With Advanced Classical Hodgkin Lymphoma
NCT01712490ACTIVE NOT RECRUITINGPHASE3
1.33K participants
INTERVENTIONAL
Birmingham, United States +214 more
Started: Nov 9, 2012
Brentuximab Vedotin in Early Stage Hodgkin Lymphoma
NCT04685616RECRUITINGPHASE3
1.04K participants
INTERVENTIONAL
Stanford, United States +64 more
Started: Apr 14, 2022
Completed Clinical Trials
10 completed trials for ABVD (Doxorubicin, Bleomycin, Vinblastine, Dacarbazine) in Hodgkin Lymphoma
FIL Study on ABVD DD-DI as Upfront Therapy in HL.
NCT03159897COMPLETEDPHASE3
500 participants
INTERVENTIONAL
Padua, Italy +45 more
Started: Aug 1, 2017
Study of a-Interferon With Adriamycin, Bleomycin, Velban, and Dacarbazine (ABVD) With Hodgkin's Disease
NCT01404936COMPLETEDPHASE2
35 participants
INTERVENTIONAL
Houston, United States
Started: Jul 1, 1996
Radiation Therapy and Chemotherapy in Treating Patients With Hodgkin's Disease
NCT00002561COMPLETEDPHASE3
405 participants
INTERVENTIONAL
Calgary, Canada +21 more
Started: Jan 25, 1994
High-dose Chemotherapy and Stem Cell Transplantation, in Patients PET-2 Positive, After 2 Courses of ABVD and Comparison of RT Versus no RT in PET-2 Negative Patients
NCT00784537COMPLETEDPHASE2, PHASE3
520 participants
INTERVENTIONAL
Aviano, Italy +26 more
Started: Sep 1, 2008
Phase 2 Study of Rituximab-ABVD in Classical Hodgkin Lymphoma
NCT00369681COMPLETEDPHASE2
51 participants
INTERVENTIONAL
Duarte, United States +3 more
Started: May 1, 2006
Rituximab and ABVD for Hodgkin's Patients
NCT00504504COMPLETEDPHASE2
85 participants
INTERVENTIONAL
Houston, United States
Started: Mar 1, 2001
Anti-CD30 (Brentuximab Vedotin) With AVD Versus ABVD Chemotherapy Protocol Frontline Therapy in Patients With Advanced Classical Hodgkin Lymphoma
NCT07171827COMPLETEDNA
60 participants
INTERVENTIONAL
Helwan, Egypt
Started: Mar 1, 2023
Dose-dense ABVD First Line Therapy in Early Stage Unfavorable Hodgkin's Lymphoma
NCT02247869COMPLETEDPHASE2
100 participants
INTERVENTIONAL
San Giovanni Rotondo, Italy +36 more
Started: Feb 1, 2012
Study Comparing ABVD vs BEACOPP in Advanced Hodgkin's Lymphoma
NCT01251107COMPLETEDPHASE3
331 participants
INTERVENTIONAL
Milan, Italy
Started: Mar 1, 2000
Combination Chemotherapy With or Without Rituximab in Treating Participants With Stage III-IV Classic Hodgkin Lymphoma
NCT00654732COMPLETEDPHASE2
58 participants
INTERVENTIONAL
Miami, United States +3 more
Started: Mar 19, 2008
Showing 20 of 48 total trials