DFDA

Cryotherapy (Liquid Nitrogen)

Treatment for Hpv Infection

Typical Dosage: Applied for 5-30 seconds, repeated weekly/bi-weekly

Effectiveness
70%
Safety Score
80%
Clinical Trials
11
Participants
10K

Comparative Safety Scale(Higher is safer)

Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
80
DangerousModerateSafe
Treatment Details
Dosage Range
Applied for 5-30 seconds, repeated weekly/bi-weekly
Time to Effect
1-4 weeks per session
Treatment Duration
Multiple sessions over 4-12 weeks
Evidence Quality
HIGH
Number Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$1,000
Side Effect Mgmt:$50
Total Annual:$1,050
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOOD
Outcome-Based Costs
Cost per Responder
$1,500
Cost per Remission
$1,500
Comparison vs Imiquimod
Cost Difference
$-200/year
Less expensive
QALY Difference
0.00 QALYs
Same outcomes
Dominance
No dominance
Cryotherapy (Liquid Nitrogen) Outcomes

for Hpv Infection

Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+70%
Remission Rate
+70%
Common Side Effects
Pain
+85%
Blistering
+60%
Ulceration
+30%
Hypopigmentation
+20%
Scarring
+7%

Sources:

cda-amc.ca
nih.gov
nih.gov

WARNING: LIMITED TRIALS AVAILABLE

You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!

Active Clinical Trials
1 active trial recruiting for Cryotherapy (Liquid Nitrogen) in Hpv Infection

Comparison of Efficacy of Topical Adaplene Gel Versus Crythotherapy in Recurrent Plantar Warts

NCT07016360RECRUITINGPHASE4
View Study
98 participants
INTERVENTIONAL
Peshawar, Pakistan
Started: Sep 15, 2025
Completed Clinical Trials
6 completed trials for Cryotherapy (Liquid Nitrogen) in Hpv Infection

Cost-effectiveness of EndWarts® FREEZE - an Alternative Home Cryotherapy Device for Wart Treatment

NCT04781244COMPLETEDNA
View Study
22 participants
INTERVENTIONAL
Bangkok Noi, Thailand
Started: Nov 12, 2020

A Trial Examining the Treatment of Common Warts With Combination Liquid Nitrogen (LN2) and Cantharidin

NCT01084824COMPLETEDNA
View Study
70 participants
INTERVENTIONAL
Coeur d'Alene, United States
Started: Jun 1, 2007

Comparison of Cryotherapy and Peeling Agent in the Treatment of Common Warts

NCT05712811COMPLETEDNA
View Study
60 participants
INTERVENTIONAL
Abbottābād, Pakistan
Started: Jun 1, 2022

Serum Galectin-3 as a Marker of Human Papillomavirus Infection

NCT06005389COMPLETED
View Study
100 participants
OBSERVATIONAL
Asyut, Egypt
Started: Dec 1, 2021

Cold Atmospheric Plasma Device for Pediatric Molluscum and Verruca

NCT05070754COMPLETEDPHASE4
View Study
17 participants
INTERVENTIONAL
Charleston, United States
Started: Dec 2, 2021

Intralesional Measles, Mumps, Rubella (MMR) Vaccine Versus Cryotherapy in Treatment of Multiple Common and Planter Warts

NCT03183765COMPLETEDPHASE4
View Study
48 participants
INTERVENTIONAL
Asyut, Egypt
Started: Aug 1, 2017