Cryotherapy (Liquid Nitrogen)
Treatment for Hpv Infection
Typical Dosage: Applied for 5-30 seconds, repeated weekly/bi-weekly
Effectiveness
70%
Safety Score
80%
Clinical Trials
11
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
80
DangerousModerateSafe
Treatment Details
Dosage Range
Applied for 5-30 seconds, repeated weekly/bi-weekly
Time to Effect
1-4 weeks per session
Treatment Duration
Multiple sessions over 4-12 weeks
Evidence Quality
HIGHNumber Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$1,000
Side Effect Mgmt:$50
Total Annual:$1,050
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODQALYs Gained
Outcome-Based Costs
Cost per Responder
$1,500
Cost per Remission
$1,500
Comparison vs Imiquimod
Cost Difference
$-200/year
Less expensive
QALY Difference
0.00 QALYs
Same outcomes
Dominance
No dominance
Cryotherapy (Liquid Nitrogen) Outcomes
for Hpv Infection
Efficacy Outcomes
Overall Effectiveness
+70%
Response Rate
+70%
Remission Rate
+70%
Common Side Effects
Pain
+85%
Blistering
+60%
Ulceration
+30%
Hypopigmentation
+20%
Scarring
+7%
Sources:
Active Clinical Trials
1 active trial recruiting for Cryotherapy (Liquid Nitrogen) in Hpv Infection
Comparison of Effectiveness of Topical Retinoids Versus Liquid Nitrogen in Treatment of Plantar Warts(Viral Infection)
NCT07016360RECRUITINGPHASE4
98 participants
INTERVENTIONAL
Peshawar, Pakistan
Started: Jun 15, 2025
Completed Clinical Trials
6 completed trials for Cryotherapy (Liquid Nitrogen) in Hpv Infection
Cost-effectiveness of EndWarts® FREEZE - an Alternative Home Cryotherapy Device for Wart Treatment
NCT04781244COMPLETEDNA
22 participants
INTERVENTIONAL
Bangkok Noi, Thailand
Started: Nov 12, 2020
A Trial Examining the Treatment of Common Warts With Combination Liquid Nitrogen (LN2) and Cantharidin
NCT01084824COMPLETEDNA
70 participants
INTERVENTIONAL
Coeur d'Alene, United States
Started: Jun 1, 2007
Comparison of Cryotherapy and Peeling Agent in the Treatment of Common Warts
NCT05712811COMPLETEDNA
60 participants
INTERVENTIONAL
Abbottābād, Pakistan
Started: Jun 1, 2022
Serum Galectin-3 as a Marker of Human Papillomavirus Infection
NCT06005389COMPLETED
100 participants
OBSERVATIONAL
Asyut, Egypt
Started: Dec 1, 2021
Cold Atmospheric Plasma Device for Pediatric Molluscum and Verruca
NCT05070754COMPLETEDPHASE4
17 participants
INTERVENTIONAL
Charleston, United States
Started: Dec 2, 2021
Intralesional Measles, Mumps, Rubella (MMR) Vaccine Versus Cryotherapy in Treatment of Multiple Common and Planter Warts
NCT03183765COMPLETEDPHASE4
48 participants
INTERVENTIONAL
Asyut, Egypt
Started: Aug 1, 2017