Valsartan
Treatment for Hypertension
Typical Dosage: 80-320mg daily
Effectiveness
86%
Safety Score
70%
Clinical Trials
258
Participants
350K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
80-320mg daily
Time to Effect
1-2 weeks
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
45(Treat 45 patients to see 1 additional successful outcome)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$30
Monitoring:$150
Side Effect Mgmt:$50
Total Annual:$230
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$10,000/QALY
QALYs Gained
0.5
Outcome-Based Costs
Cost per Responder
$383
Comparison vs No treatment
Cost Difference
$-230/year
Less expensive
QALY Difference
+0.50 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
Valsartan Outcomes
for Hypertension
Efficacy Outcomes
Overall Effectiveness
+86%
Response Rate
+60%
Common Side Effects
Dizziness/Orthostatic Hypotension
+5%
Hyperkalemia
+3%
Renal impairment
+2%
Angioedema
+0.05%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
14 completed trials for Valsartan in Hypertension
To Demonstrate Non-inferiority of Combination of 5 mg Amlodipine/ 80 mg Valsartan to 160 mg Valsartan Alone
NCT01070043COMPLETEDPHASE4
60 participants
INTERVENTIONAL
Taipei, Taiwan
Started: Jun 1, 2009
A Bioequivalence Study Comparing Cilnidipine/Valsartan Combination With Coadministration of Cilnidipine and Valsartan
NCT02343250COMPLETEDPHASE1
54 participants
INTERVENTIONAL
Started: Mar 1, 2015
A Study to Evaluate the Long-term Use of Valsartan in Children 6 Months to 5 Years Old With Hypertension
NCT00457626COMPLETEDPHASE3
66 participants
INTERVENTIONAL
Hackensack, United States +35 more
Started: Apr 9, 2007
Double-dose Valsartan Monotherapy in Hypertension Treatment: an Effectiveness and Safety Evaluation in Chinese Patients.
NCT01541189COMPLETEDPHASE4
200 participants
INTERVENTIONAL
Beijing, China
Started: Feb 1, 2012
A Study Comparing Valsartan With And Without Hydrochlorothiazide In Patients With Hypertension
NCT00241007COMPLETEDPHASE3
836 participants
INTERVENTIONAL
East Hanover, United States
Started: Dec 1, 2003
Efficacy and Safety of Valsartan/Hydrochlorothiazide Combination Compared to Valsartan Monotherapy or Hydrochlorothiazide Monotherapy in Elderly (>70) With Mild-moderate Hypertension.
NCT00698646COMPLETEDPHASE4
384 participants
INTERVENTIONAL
Birmingham, United States +19 more
Started: Apr 1, 2008
24 Hour Ambulatory Cardiac Oxygen Consumption
NCT05170061COMPLETEDPHASE3
26 participants
INTERVENTIONAL
Buffalo, United States
Started: Feb 1, 2013
A Study to Compare Treating Hypertension With Valsartan 160 MG to Valsartan 320 Mg
NCT00241137COMPLETEDPHASE3
3.79K participants
INTERVENTIONAL
Investigative Centers, Germany
Started: Sep 1, 2003
A Study to Describe Vascular and Renal Effects and Safety of Valsartan in Patients With High Blood Pressure
NCT00171353COMPLETEDPHASE4
109 participants
INTERVENTIONAL
Basel, Switzerland
Started: Jul 1, 2004
Comparative Study of Valsartan and Amlodipine Versus Amlodipine Alone in Hypertension
NCT00333489COMPLETEDPHASE4
551 participants
INTERVENTIONAL
Basel, Switzerland
Started: Mar 1, 2004
A Study Of Valsartan Used To Treat Hypertension For Up To 56 Weeks In Children Ages 1 - 5 Years Who Have Hypertension
NCT00171028COMPLETEDPHASE3
90 participants
INTERVENTIONAL
East Hanover, United States
Started: Dec 1, 2003
8 Weeks Study to Evaluate the Efficacy and Safety of Valsartan in Combination With Aliskiren Compared to Valsartan Alone in Patients With Stage 2 Hypertension
NCT00809926COMPLETEDPHASE4
451 participants
INTERVENTIONAL
East Hanover, United States
Started: Jan 1, 2009
A Study Of Valsartan Used To Treat Hypertension For Up To 13 Months In Hypertensive Children Ages 6 - 16 Years Of Age
NCT00171041COMPLETEDPHASE3
265 participants
INTERVENTIONAL
E.Hanover, United States +1 more
Started: Dec 1, 2002
Low-dose Nifedipine-Valsartan Combination Compared to Up-titrated Valsartan Monotherapy in Essential Hypertension
NCT00993109COMPLETEDPHASE4
360 participants
INTERVENTIONAL
Guangzhou, China +16 more
Started: Feb 1, 2010
Showing 20 of 260 total trials