Hydrochlorothiazide (Thiazide Diuretic)
Treatment for Hypertensive Heart Disease
Typical Dosage: 12.5mg - 50mg daily
Effectiveness
87%
Safety Score
70%
Clinical Trials
1
Participants
1.5M
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
12.5mg - 50mg daily
Time to Effect
2-4 weeks for full BP effect
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
12(Treat 12 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
96%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$20
Monitoring:$350
Side Effect Mgmt:$50
Total Annual:$420
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$5,000/QALY
QALYs Gained
2.6
Outcome-Based Costs
Cost per Responder
$525
Comparison vs Lisinopril (ACE Inhibitor)
Cost Difference
$-10/year
Less expensive
QALY Difference
-0.05 QALYs
Worse outcomes
Dominance
No dominance
Hydrochlorothiazide (Thiazide Diuretic) Outcomes
for Hypertensive Heart Disease
Efficacy Outcomes
Overall Effectiveness
+87%
Response Rate
+80%
Common Side Effects
Hypokalemia
+10%
Dizziness
+5%
Hyperuricemia
+10%
Hyperglycemia
+5%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov